Developing biomedical engineering technologies for reproductive medicine

Y Zhu, B Kong, R Liu, Y Zhao - Smart Medicine, 2022 - Wiley Online Library
Infertility is a rising global health issue with a far‐reaching impact on the socioeconomic
livelihoods. As there are highly complex causes of male and female infertility, it is highly …

Asherman's syndrome: current perspectives on diagnosis and management

E Dreisler, JJ Kjer - International journal of women's health, 2019 - Taylor & Francis
Intrauterine adhesions with symptoms like hypomenorrhea or infertility are known under the
term Asherman's syndrome. Although the syndrome has been widely investigated, evidence …

Allogeneic cell therapy using umbilical cord MSCs on collagen scaffolds for patients with recurrent uterine adhesion: a phase I clinical trial

Y Cao, H Sun, H Zhu, X Zhu, X Tang, G Yan… - Stem cell research & …, 2018 - Springer
Background Intrauterine adhesions (IUA) are the most common cause of uterine infertility
and are caused by endometrium fibrotic regeneration following severe damage to the …

[HTML][HTML] In situ delivery of apoptotic bodies derived from mesenchymal stem cells via a hyaluronic acid hydrogel: a therapy for intrauterine adhesions

L Xin, C Wei, X Tong, Y Dai, D Huang, J Chen, L Ma… - Bioactive materials, 2022 - Elsevier
Stem cell-based and stem cell-derived exosome-based therapies have shown promising
potential for endometrial regeneration and the clinical treatment of intrauterine adhesions …

Endometrial and menstrual blood mesenchymal stem/stromal cells: biological properties and clinical application

M Bozorgmehr, S Gurung, S Darzi, S Nikoo… - Frontiers in cell and …, 2020 - frontiersin.org
A highly proliferative mesenchymal stem/stromal cell (MSC) population was recently
discovered in the dynamic, cyclically regenerating human endometrium as clonogenic …

Stem cell-based therapy for ameliorating intrauterine adhesion and endometrium injury

YT Song, PC Liu, J Tan, CY Zou, QJ Li, J Li-Ling… - Stem Cell Research & …, 2021 - Springer
Intrauterine adhesion refers to endometrial repair disorders which are usually caused by
uterine injury and may lead to a series of complications such as abnormal menstrual …

[HTML][HTML] Stem cell therapy in Asherman syndrome and thin endometrium: Stem cell-based therapy

R Azizi, L Aghebati-Maleki, M Nouri, F Marofi… - Biomedicine & …, 2018 - Elsevier
The endometrium is one of the essential components of the uterus. The endometrium of
human is a complex and dynamic tissue, which undergoes periods of growth and turn over …

The multi-functional roles of menstrual blood-derived stem cells in regenerative medicine

L Chen, J Qu, C Xiang - Stem cell research & therapy, 2019 - Springer
Menstrual blood-derived stem cells (MenSCs) are a novel source of mesenchymal stem
cells (MSCs). MenSCs are attracting more and more attention since their discovery in 2007 …

Therapeutic options and drug delivery strategies for the prevention of intrauterine adhesions

L Kou, X Jiang, S Xiao, YZ Zhao, Q Yao… - Journal of Controlled …, 2020 - Elsevier
Intrauterine adhesions (IUAs) are bands of fibrous tissue that form in the endometrial cavity
and associated with the increased risk of abnormal menstruation, recurrent pregnancy loss …

Application of stem cell therapy for infertility

S Saha, P Roy, C Corbitt, SS Kakar - Cells, 2021 - mdpi.com
Infertility creates an immense impact on the psychosocial wellbeing of affected couples,
leading to poor quality of life. Infertility is now considered to be a global health issue …