A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …

Spermatogenesis is a complex process of proliferation and differentiation during male germ
cell development involving mitosis, meiosis and spermiogenesis. Endogenous and …

Hormonal regulation is essential to spermatogenesis. Sertoli cells (SCs) have functions that
reach far beyond the physical support of germ cells, as they are responsible for creating the …

Spermiation—the release of mature spermatozoa from Sertoli cells into the seminiferous
tubule lumen—occurs by the disruption of an anchoring device known as the apical …

Male reproductive health has deteriorated considerably in the last few decades. Nutritional,
socioeconomic, lifestyle and environmental factors (among others) have been attributed to …

Di-(2-ethylhexyl) phthalate (DEHP) is the most commonly used phthalate, and it is an
endocrine-disrupting chemical. This study tested a hypothesis that prenatal exposure to …

ABSTRACT Bisphenol A [2, 2-bis (4-hydroxyphenyl) propane](BPA), 4-nonylphenol (NP)
and di (2-ethylhexyl) phthalate (DEHP), and its metabolite mono-2-ethylhexyl phthalate …

Estrogens, through their receptors, play an important role in regulation of spermatogenesis.
However, the precise role of the estrogen receptors (ESR1 and ESR2) has been difficult to …

The aim of the present study was to investigate the intracellular signaling events
downstream of the classical estrogen receptors (ESRs) and G protein-coupled estrogen …

Several processes including oxidative stress, apoptosis, inflammation and autophagy are
related to testicular function. Recent studies indicate that a crosstalk between apoptosis and …