Vitamin D, infections and immunity
A Ismailova, JH White - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Vitamin D, best known for its role in skeletal health, has emerged as a key regulator of innate
immune responses to microbial threat. In immune cells such as macrophages, expression of …
immune responses to microbial threat. In immune cells such as macrophages, expression of …
Emerging roles of vitamin D-induced antimicrobial peptides in antiviral innate immunity
JH White - Nutrients, 2022 - mdpi.com
Vitamin D deficiency, characterized by low circulating levels of calcifediol (25-
hydroxyvitamin D, 25D) has been linked to increased risk of infections of bacterial and viral …
hydroxyvitamin D, 25D) has been linked to increased risk of infections of bacterial and viral …
Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia
Influenza viruses constitute a major health threat and economic burden globally, frequently
exacerbated by preexisting or rapidly emerging resistance to antiviral therapeutics. To …
exacerbated by preexisting or rapidly emerging resistance to antiviral therapeutics. To …
A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger …
AO Aliprantis, CA Shaw, P Griffin… - Human vaccines & …, 2021 - Taylor & Francis
ABSTRACT Respiratory Syncytial Virus (RSV) causes lower respiratory tract infections that
can be severe and sometimes fatal. The risk for severe RSV infection is highest in infants …
can be severe and sometimes fatal. The risk for severe RSV infection is highest in infants …
Metal nanoparticles: a promising treatment for viral and arboviral infections
K Maduray, R Parboosing - Biological Trace Element Research, 2021 - Springer
Globally, viral diseases continue to pose a significant threat to public health. Recent
outbreaks, such as influenza, coronavirus, Ebola, and dengue, have emphasized the urgent …
outbreaks, such as influenza, coronavirus, Ebola, and dengue, have emphasized the urgent …
A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein
A Tang, Z Chen, KS Cox, HP Su, C Callahan… - Nature …, 2019 - nature.com
Respiratory syncytial virus (RSV) infection is the leading cause of hospitalization and infant
mortality under six months of age worldwide; therefore, the prevention of RSV infection in all …
mortality under six months of age worldwide; therefore, the prevention of RSV infection in all …
Pre-fusion F is absent on the surface of formalin-inactivated respiratory syncytial virus
AM Killikelly, M Kanekiyo, BS Graham - Scientific reports, 2016 - nature.com
The lack of a licensed vaccine for respiratory syncytial virus (RSV) can be partly attributed to
regulatory hurdles resulting from vaccine enhanced respiratory disease (ERD) subsequent …
regulatory hurdles resulting from vaccine enhanced respiratory disease (ERD) subsequent …
Nanostructures for prevention, diagnosis, and treatment of viral respiratory infections: from influenza virus to SARS-CoV-2 variants
Viruses are a major cause of mortality and socio-economic downfall despite the plethora of
biopharmaceuticals designed for their eradication. Conventional antiviral therapies are often …
biopharmaceuticals designed for their eradication. Conventional antiviral therapies are often …
EGFR interacts with the fusion protein of respiratory syncytial virus strain 2-20 and mediates infection and mucin expression
MG Currier, S Lee, CC Stobart, AL Hotard… - PLoS …, 2016 - journals.plos.org
Respiratory syncytial virus (RSV) is the major cause of viral lower respiratory tract illness in
children. In contrast to the RSV prototypic strain A2, clinical isolate RSV 2–20 induces …
children. In contrast to the RSV prototypic strain A2, clinical isolate RSV 2–20 induces …