Coronary atherosclerosis is by far the most frequent cause of ischemic heart disease, and
plaque disruption with superimposed thrombosis is the main cause of the acute coronary …

The incidence of cardiovascular disease differs significantly between men and women, in
part because of differences in risk factors and hormones. 1 The incidence of atherosclerotic …

Objectives. This study assessed whether aging is associated with progressive endothelial
dysfunction, whether the pattern of any age-related decline in vascular health is different in …

The impact of estrogen exposure in preventing or treating cardiovascular disease is
controversial. But it is clear that estrogen has important effects on vascular physiology and …

Gender has an important influence on blood pressure, with premenopausal women having a
lower arterial blood pressure than age-matched men. Compared with premenopausal …

Estrogen is an important vasoprotective molecule that causes the rapid dilation of blood
vessels by activating endothelial nitric oxide synthase (eNOS) through an unknown …

Background Estrogen has been reported to augment endothelium-dependent
vasodilatation. The role of endogenous ovarian hormones in modulating endothelium …

Myocardial infarction is the most frequent cause of mortality in the United States as well as in
most western countries. In this review, the processes leading to myocardial infarction are …

Sex has a profound impact on myocardial remodeling, which is defined as the molecular
and cellular events after an injury to the myocardium (ie, necrosis, pressure overload …

Over the past decade, clinical and basic research has demonstrated that estrogen has a
dramatic impact on the response to vascular injury and the development of atherosclerosis …