The precise orchestration of hormonal regulation at all levels of the hypothalamic-pituitary-
gonadal axis is essential for normal reproductive function and fertility. The pulsatile secretion …

BACKGROUND Human reproduction depends on an intact hypothalamic–pituitary–gonadal
(HPG) axis. Hypothalamic gonadotrophin-releasing hormone (GnRH) has been recognized …

Polycystic ovary syndrome (PCOS) is the most common endocrinopathies affecting the early
reproductive age in women, whose pathophysiology perplexes many researchers till today …

Identification of novel neurohormones that regulate the reproductive axis is essential for the
progress of neuroendocrinology. The decapeptide gonadotropin-releasing hormone (GnRH) …

Fish have been of paramount importance to our understanding of vertebrate comparative
neuroendocrinology and the mechanisms underlying the physiology and evolution of …

Mammalian reproductive cycles are controlled by an intricate interplay between the
hypothalamus, pituitary and gonads. Central to the function of this axis is the ability of the …

Follicle-stimulating hormone (FSH) plays fundamental roles in male and female fertility. FSH
is a heterodimeric glycoprotein expressed by gonadotrophs in the anterior pituitary. The …

The pituitary gonadotropin hormones, FSH and LH, are essential for fertility. Containing an
identical α-subunit (CGA), they are comprised of unique β-subunits, FSHβ and LHβ …

The hypothalamic–pituitary–gonadal axis (HPG) plays vital roles in reproduction and steroid
hormone production in both sexes. The focus of this review is upon gene structures, receptor …

The precise interplay of hormonal influences that governs gonadotropin hormone production
by the pituitary includes endocrine, paracrine and autocrine actions of hypothalamic …