The gut microbiota in the first decade of life

M Derrien, AS Alvarez, WM de Vos - Trends in microbiology, 2019 - cell.com
Appreciation of the importance of the gut microbiome is growing, and it is becoming
increasingly relevant to identify preventive or therapeutic solutions targeting it. The …

Changing global epidemiology of inflammatory bowel diseases: sustaining health care delivery into the 21st century

AN Ananthakrishnan, GG Kaplan, SC Ng - Clinical Gastroenterology and …, 2020 - Elsevier
Crohn's disease and ulcerative colitis have emerged as global diseases. They affect over 2
million individuals in the North America, 3.2 million in Europe, and millions more worldwide …

Malnutrition and gut microbiota in children

I Iddrisu, A Monteagudo-Mera, C Poveda, S Pyle… - Nutrients, 2021 - mdpi.com
Malnutrition continues to threaten the lives of millions across the world, with children being
hardest hit. Although inadequate access to food and infectious disease are the primary …

Environmental risk factors for inflammatory bowel disease

N Singh, CN Bernstein - United European gastroenterology …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic, progressive immune‐mediated inflammatory
condition of the gastrointestinal tract. Environmental risk factors play a role in developing …

Early life exposures and the risk of inflammatory bowel disease: systematic review and meta-analyses

M Agrawal, J Sabino, C Frias-Gomes… - …, 2021 - thelancet.com
Background Early life exposures impact immune system development and therefore the risk
of immune-mediated diseases, including inflammatory bowel disease (IBD). We …

The epidemiology of inflammatory bowel disease: clues to pathogenesis?

SM Borowitz - Frontiers in Pediatrics, 2023 - frontiersin.org
Historically, inflammatory bowel disease (IBD) was most common in North America and
Europe and more common with a north-south gradient. Over the past century, there has …

[HTML][HTML] Extracellular vesicles: the next generation theranostic nanomedicine for inflammatory bowel disease

D Li, M Yang, J Xu, H Xu, M Zhu, Y Liang… - International journal …, 2022 - ncbi.nlm.nih.gov
The recent rapid development in the field of extracellular vesicles (EVs) based
nanotechnology has provided unprecedented opportunities for nanomedicine platforms. As …

Exosome-induced regulation in inflammatory bowel disease

H Zhang, L Wang, C Li, Y Yu, Y Yi, J Wang… - Frontiers in …, 2019 - frontiersin.org
An exosome (30–150 nm size) is a cell-derived vesicle. Exosome-induced regulation in
inflammatory bowel disease (IBD) is becoming increasingly popular due to their potential …

Targeting JAK/STAT signaling pathways in treatment of inflammatory bowel disease

L Wang, Y Hu, B Song, Y Xiong, J Wang, D Chen - Inflammation Research, 2021 - Springer
Janus kinase/signal transduction and transcriptional activator (JAK/STAT) signaling pathway
is a transport hub for cytokine secretion and exerts its effects. The activation of JAK/STAT …

Fusobacterium nucleatum aggravates ulcerative colitis through promoting gut microbiota dysbiosis and dysmetabolism

S Lin, X Zhang, X Zhu, J Jiao, Y Wu… - Journal of …, 2023 - Wiley Online Library
Background The correlation between periodontitis and ulcerative colitis (UC) has drawn
widespread attention recently. Fusobacterium nucleatum (F. nucleatum) as a periodontal …