Implications of oxidative stress and cell membrane lipid peroxidation in human cancer (Spain)

P Cejas, E Casado, C Belda-Iniesta, J De Castro… - Cancer Causes & …, 2004 - Springer
Abstract Reactive Oxygen Species (ROS) result from cell metabolism as well as from
extracellular processes. ROS exert some functions necessary for cell homeostasis …

Anti-tumor activity of wogonin, an extract from Scutellaria baicalensis, through regulating different signaling pathways

N Sharma, AK Singh, SS Sodhi, JJ Zhang… - Chinese Journal of …, 2017 - Elsevier
Wogonin is a plant flavonoid compound extracted from Scutellaria baicalensis (Huang-Qin
or Chinese skullcap) and has been studied thoroughly by many researchers till date for its …

Prostaglandin E2 secreted by thyroid cancer cells contributes to immune escape through the suppression of natural killer (NK) cell cytotoxicity and NK cell …

A Park, Y Lee, MS Kim, YJ Kang, YJ Park… - Frontiers in …, 2018 - frontiersin.org
Natural killer (NK) cells play important roles in immune surveillance. However, the tumor
microenvironment suppresses NK cell function and allows cancer cells to evade immune …

Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling …

JT Hwang, J Ha, OJ Park - Biochemical and biophysical research …, 2005 - Elsevier
5-Fluorouracil (5-FU) is one of the widely used chemotherapeutic drugs targeting various
cancers, but its chemo-resistance remains as a major obstacle in clinical settings. In the …

A multicenter randomized phase II study of sequential epirubicin/cyclophosphamide followed by docetaxel with or without celecoxib or trastuzumab according to HER2 …

JY Pierga, S Delaloge, M Espié, E Brain… - Breast cancer research …, 2010 - Springer
To assess anti-tumor activity of sequential epirubicin/cyclophosphamide followed by
docetaxel with the randomized addition of celecoxib in HER2 negative patients or …

[HTML][HTML] Pancreatic stellate cells and fibrosis

P Phillips - 2012 - europepmc.org
Pancreatic cancer is characterised by a prominent desmoplastic/stromal reaction. It is now
known that pancreatic stellate cells (PSCs) are the principal source of fibrosis in the stroma …

Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering

N Vunnam, MC Young, EE Liao, CH Lo… - Cancer Biology & …, 2023 - Taylor & Francis
Nimesulide is a nonsteroidal anti-inflammatory drug and a COX-2 inhibitor with antitumor
and antiproliferative activities that induces apoptosis in oral, esophagus, breast, and …

Expression of Cox-1 and Cox-2 in canine mammary tumours

FL Queiroga, A Alves, I Pires, C Lopes - Journal of comparative pathology, 2007 - Elsevier
The aim of this study was to investigate immunohistochemically the expression of
cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) in canine mammary tumours of …

COX-1 and COX-2 expression in canine cutaneous, oral and ocular melanocytic tumours

I Pires, A Garcia, J Prada, FL Queiroga - Journal of comparative pathology, 2010 - Elsevier
In order to evaluate the potential value of non-steroidal anti-inflammatory drugs (NSAIDs) in
the treatment of canine malignant melanoma, expression of cyclooxygenase (COX)-1 and …

Downregulation of signalling molecules involved in angiogenesis of prostate cancer cell line (PC-3) by kombucha (lyophilized)

T Srihari, R Arunkumar, J Arunakaran… - … & Preventive Nutrition, 2013 - Elsevier
Kombucha is a fermented tea beverage produced by fermenting sugared black tea with tea
fungus (kombucha). Prostate cancer like other solid tumours is also angiogenesis …