Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76
JCC76 is a derivative of cyclooxygenase-2 (COX-2) selective inhibitor nimesulide and
exhibits potent anti-breast cancer activity. It selectively induces apoptosis of Her2 positive …
exhibits potent anti-breast cancer activity. It selectively induces apoptosis of Her2 positive …
Synergistic growth inhibitory effect of deracoxib with doxorubicin against a canine mammary tumor cell line, CMT-U27
Cyclooxygenase (COX) inhibitors have been shown to exert anti-angiogenic and anti-tumor
activities on many types of malignant tumors. These anticancer properties make it …
activities on many types of malignant tumors. These anticancer properties make it …
A possible role for cyclooxygenase 2 inhibitors in the treatment of chronic urticaria
MK Anand, HS Nelson, SC Dreskin - Journal of allergy and clinical …, 2003 - jacionline.org
Mast cell degranulation resulting in histamine release is a key factor in chronic urticaria. 1, 2
It is unknown, however, whether production of prostaglandins and cysteinyl leukotrienes by …
It is unknown, however, whether production of prostaglandins and cysteinyl leukotrienes by …
Differential role for phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate-stimulated MAPK activation, Cox-2 and IL-8 expression
Phospholipase D (PLD) is expressed in many tissues and stimulated by growth factors and
cytokines. However, the role of PLD in signal transduction is still not well-understood …
cytokines. However, the role of PLD in signal transduction is still not well-understood …
Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
L Pavliv - US Patent 6,727,286, 2004 - Google Patents
The present invention provides a pharmaceutical composition comprising an aqueous
solution of arginine and ibuprofen, wherein the molar ratio of arginine to ibuprofen is less …
solution of arginine and ibuprofen, wherein the molar ratio of arginine to ibuprofen is less …
Antiangiogenesis: a possible treatment option for prostate cancer?
RL Longoria, MC Cox, WD Figg - Clinical Genitourinary Cancer, 2005 - Elsevier
With a need for effective treatment modalities in prostate cancer, angiogenesis is a likely
target for the interference of tumor progression. Angiogenesis promotes the vasculature of a …
target for the interference of tumor progression. Angiogenesis promotes the vasculature of a …
COX-2 and angiogenesis in gastric cancer
Z Walther - Journal of clinical gastroenterology, 2003 - journals.lww.com
Most epithelial cancers, including those of the digestive tract, show overexpression of COX-
2, an inducible enzyme controlling prostaglandin synthesis. The upregulation of COX-2 in …
2, an inducible enzyme controlling prostaglandin synthesis. The upregulation of COX-2 in …
Molecular targets in cancer therapy
DM Gale - Seminars in oncology nursing, 2003 - Elsevier
OBJECTIVES:: To review selected pharmacologic agents that target key cellular processes
along with their mechanisms of action and adverse events. Nursing implications including …
along with their mechanisms of action and adverse events. Nursing implications including …
[HTML][HTML] Effects of adenovirus-mediated human cyclooxygenase-2 antisense RNA on the growth of hepatocellular carcinoma
XH Wang, SB Li, Q Tong, GJ Xie… - World Journal of …, 2005 - ncbi.nlm.nih.gov
AIM: To investigate the relation between the expression of cyclooxygenase-2 (COX-2) and
liver cancer, to construct the recombinant adenovirus encoding human COX-2 antisense …
liver cancer, to construct the recombinant adenovirus encoding human COX-2 antisense …