Oral administration of marine collagen peptides prepared from chum salmon (Oncorhynchus keta) improves wound healing following cesarean section in rats

J Wang, M Xu, R Liang, M Zhao, Z Zhang… - Food & Nutrition …, 2015 - Taylor & Francis
Background The goal of the present study was to investigate the wound-healing potential of
marine collagen peptides (MCPs) from chum salmon skin administered to rats following …

Analysis of serum inflammatory mediators identifies unique dynamic networks associated with death and spontaneous survival in pediatric acute liver failure

N Azhar, C Ziraldo, D Barclay, DA Rudnick… - PloS one, 2013 - journals.plos.org
Background Tools to predict death or spontaneous survival are necessary to inform liver
transplantation (LTx) decisions in pediatric acute liver failure (PALF), but such tools are not …

Systems biology of fungal infection

F Horn, T Heinekamp, O Kniemeyer… - Frontiers in …, 2012 - frontiersin.org
Elucidation of pathogenicity mechanisms of the most important human-pathogenic fungi,
Aspergillus fumigatus and Candida albicans, has gained great interest in the light of the …

[HTML][HTML] Use of systems biology to decipher host–pathogen interaction networks and predict biomarkers

A Dix, S Vlaic, R Guthke, J Linde - Clinical Microbiology and Infection, 2016 - Elsevier
In systems biology, researchers aim to understand complex biological systems as a whole,
which is often achieved by mathematical modelling and the analyses of high-throughput …

Computational systems mechanobiology of wound healing

AB Tepole - Computer methods in applied mechanics and …, 2017 - Elsevier
Achieving perfect skin regeneration after wounding remains challenging because of the lack
of fundamental understanding of the harmonious interplay among different cell types …

A Multiscale Agent-Based in silico Model of Liver Fibrosis Progression

J Dutta-Moscato, A Solovyev, Q Mi… - … in bioengineering and …, 2014 - frontiersin.org
Chronic hepatic inflammation involves a complex interplay of inflammatory and mechanical
influences, ultimately manifesting in a characteristic histopathology of liver fibrosis. We …

Translational systems approaches to the biology of inflammation and healing

Y Vodovotz, G Constantine, J Faeder, Q Mi… - …, 2010 - Taylor & Francis
Inflammation is a complex, non-linear process central to many of the diseases that affect
both developed and emerging nations. A systems-based understanding of inflammation …

A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine

G Nieman, D Brown, J Sarkar, B Kubiak… - Critical care …, 2012 - journals.lww.com
Objective: To gain insights into individual variations in acute inflammation and physiology.
Design: Large-animal study combined with mathematical modeling. Setting: Academic large …

A systems model for immune cell interactions unravels the mechanism of inflammation in human skin

NV Valeyev, C Hundhausen, Y Umezawa… - PLoS computational …, 2010 - journals.plos.org
Inflammation is characterized by altered cytokine levels produced by cell populations in a
highly interdependent manner. To elucidate the mechanism of an inflammatory reaction, we …

Computational modeling of chemo-bio-mechanical coupling: a systems-biology approach toward wound healing

A Buganza Tepole, E Kuhl - Computer methods in biomechanics …, 2016 - Taylor & Francis
Wound healing is a synchronized cascade of chemical, biological, and mechanical
phenomena, which act in concert to restore the damaged tissue. An imbalance between …