Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z Jin, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

[HTML][HTML] Lipid nanoparticles as delivery vehicles for inhaled therapeutics

EWX Leong, R Ge - Biomedicines, 2022 - mdpi.com
Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery.
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …

[HTML][HTML] Inhalable exosomes outperform liposomes as mRNA and protein drug carriers to the lung

KD Popowski, BL de Juan Abad, A George… - Extracellular …, 2022 - Elsevier
Respiratory diseases are among the leading causes of morbidity and mortality worldwide,
coupled with the ongoing coronavirus disease 2019 (COVID-19) pandemic. mRNA lipid …

Therapeutic supramolecular polymers: Designs and applications

H Wang, J Mills, B Sun, H Cui - Progress in Polymer Science, 2023 - Elsevier
The self-assembly of low-molecular-weight building motifs into supramolecular polymers
has unlocked a new realm of materials with distinct properties and tremendous potential for …

Emerging delivery approaches for targeted pulmonary fibrosis treatment

R Diwan, HN Bhatt, E Beaven, M Nurunnabi - Advanced drug delivery …, 2023 - Elsevier
Pulmonary fibrosis (PF) is a progressive, and life-threatening interstitial lung disease which
causes scarring in the lung parenchyma and thereby affects architecture and functioning of …

Collagen-binding peptide-enabled supramolecular hydrogel design for improved organ adhesion and sprayable therapeutic delivery

CF Anderson, RW Chakroun, ME Grimmett… - Nano …, 2022 - ACS Publications
Spraying serves as an attractive, minimally invasive means of administering hydrogels for
localized delivery, particularly due to high-throughput deposition of therapeutic depots over …

[HTML][HTML] Aerosol pulmonary immune engineering

ER Sudduth, M Trautmann-Rodriguez, N Gill… - Advanced Drug Delivery …, 2023 - Elsevier
Aerosolization of immunotherapies poses incredible potential for manipulating the local
mucosal-specific microenvironment, engaging specialized pulmonary cellular defenders …

Inhalable nanoparticles delivery targeting alveolar macrophages for the treatment of pulmonary tuberculosis

J Chae, Y Choi, M Tanaka, J Choi - Journal of bioscience and …, 2021 - Elsevier
Pulmonary tuberculosis is a highly prevalent respiratory disease that affects approximately a
quarter of the world's population. The drug treatment protocol for tuberculosis is complex …

Glyco-nanoparticles: New drug delivery systems in cancer therapy

H Khan, HR Mirzaei, A Amiri, EK Akkol… - Seminars in cancer …, 2021 - Elsevier
Cancer is known as one of the most common diseases that are associated with high mobility
and mortality in the world. Despite several efforts, current cancer treatment modalities often …