[HTML][HTML] Chondrosarcoma: a rare misfortune in aging human cartilage? The role of stem and progenitor cells in proliferation, malignant degeneration and therapeutic …

KA Boehme, SB Schleicher, F Traub… - International journal of …, 2018 - mdpi.com
Unlike other malignant bone tumors including osteosarcomas and Ewing sarcomas with a
peak incidence in adolescents and young adults, conventional and dedifferentiated …

[HTML][HTML] Osteoarthritis year in review 2018: genetics and epigenetics

MA Jeffries - Osteoarthritis and cartilage, 2019 - Elsevier
Objective This review was designed to identify highlights of the osteoarthritis (OA) genetics
and epigenetics literature published between April 2017 and January 2018. Design A …

[HTML][HTML] Comparison of the major cell populations among osteoarthritis, Kashin–Beck disease and healthy chondrocytes by single-cell RNA-seq analysis

X Wang, Y Ning, P Zhang, B Poulet, R Huang… - Cell Death & …, 2021 - nature.com
Chondrocytes are the key target cells of the cartilage degeneration that occurs in Kashin–
Beck disease (KBD) and osteoarthritis (OA). However, the heterogeneity of articular cartilage …

[HTML][HTML] Osteoarthritis year in review 2017: genetics and epigenetics

MJ Peffers, P Balaskas, A Smagul - Osteoarthritis and cartilage, 2018 - Elsevier
Objective The purpose of this review is to describe highlights from original research
publications related to osteoarthritis (OA), epigenetics and genomics with the intention of …

[HTML][HTML] Cathelicidin antimicrobial peptide (CAMP) gene promoter methylation induces chondrocyte apoptosis

G Wang, Y Li, G Yang, T Yang, L He, Y Wang - Human Genomics, 2021 - Springer
Objective The occurrence of osteoarthritis is related to genetic and environmental factors.
Among them, the change of chondrocyte gene expression pattern regulated by epigenetic …

[HTML][HTML] Epigenetics as a therapeutic target in osteoarthritis

C Núñez-Carro, M Blanco-Blanco… - Pharmaceuticals, 2023 - mdpi.com
Osteoarthritis (OA) is a heterogenous, complex disease affecting the integrity of diarthrodial
joints that, despite its high prevalence worldwide, lacks effective treatment. In recent years it …

[HTML][HTML] Genome-Wide Differentially Methylated Region Analysis to Reveal Epigenetic Differences of Articular Cartilage in Kashin–Beck Disease and Osteoarthritis

Y Fan, D Gao, Y Zhang, J Zhu, F Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Kashin–Beck disease (KBD) is a degenerative osteoarticular disorder, and displays the
significant differences with osteoarthritis (OA) regarding the etiology and molecular changes …

[HTML][HTML] Pathway-based network analyses and candidate genes associated with Kashin-Beck disease

R Zhang, H Guo, X Yang, D Zhang, B Li, Z Li, Y Xiong - Medicine, 2019 - journals.lww.com
Pathway-based network analyses and candidate genes associate... : Medicine Pathway-based
network analyses and candidate genes associated with Kashin-Beck disease : Medicine Log …

Identification of cell-specific epigenetic patterns associated with chondroitin sulfate treatment response in an endemic arthritis, Kashin-Beck disease

B Cheng, C Wu, W Wei, H Niu, Y Wen, C Li… - Bone & Joint …, 2024 - boneandjoint.org.uk
Identification of cell-specific epigenetic patterns associated with chondroitin sulfate treatment
response in an endemic arthrit Page 1 Identification of cell-specific epigenetic patterns …

Genome-wide DNA methylation profiling of hip articular cartilage identifies differentially methylated loci associated with osteonecrosis of the femoral head

J Wu, Y Du, J Song, X Dang, K Wang, Y Wen, F Zhang… - Bone, 2019 - Elsevier
Objective Recent studies demonstrated a critical role of hip articular cartilage destruction in
the development of osteonecrosis of the femoral head (ONFH). The aim of this study was to …