Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application

T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

Recent trends in molecular aggregates: An exploration of biomedicine

J Heo, DP Murale, HY Yoon, V Arun, S Choi, E Kim… - …, 2022 - Wiley Online Library
Molecular aggregates are receiving tremendous attention, demonstrating immense potential
for biomedical applications in vitro and in vivo. For instance, the molecular aggregates of …

[HTML][HTML] Designer DNA nanostructures for therapeutics

S Jiang, Z Ge, S Mou, H Yan, C Fan - Chem, 2021 - cell.com
The field of structural DNA nanotechnology applies the programmability of Watson-Crick
base pairing to the construction of custom nanostructures that are prescribed by the …

[HTML][HTML] Tetrahedral DNA nanostructures for effective treatment of cancer: advances and prospects

J Yan, X Zhan, Z Zhang, K Chen, M Wang… - Journal of …, 2021 - Springer
Recently, DNA nanostructures with vast application potential in the field of biomedicine,
especially in drug delivery. Among these, tetrahedral DNA nanostructures (TDN) have …

[HTML][HTML] Advances in biological applications of self-assembled DNA tetrahedral nanostructures

S Li, T Tian, T Zhang, X Cai, Y Lin - Materials Today, 2019 - Elsevier
In recent years, there has been a rapid progress in the development of DNA nanomaterials
for biological applications. Owing to their unsurpassed editability, various DNA …

[HTML][HTML] Advances in regenerative medicine applications of tetrahedral framework nucleic acid-based nanomaterials: an expert consensus recommendation

Y Lin, Q Li, L Wang, Q Guo, S Liu, S Zhu… - International Journal of …, 2022 - nature.com
With the emergence of DNA nanotechnology in the 1980s, self-assembled DNA
nanostructures have attracted considerable attention worldwide due to their inherent …

DNA tetrahedron nanostructures for biological applications: biosensors and drug delivery

N Xie, S Liu, X Yang, X He, J Huang, K Wang - Analyst, 2017 - pubs.rsc.org
With the rapid development of DNA nanotechnology, various DNA nanostructures with
different shapes and sizes have been self-assembled using “bottom-up” fabrication …

[HTML][HTML] DNA based and stimuli-responsive smart nanocarrier for diagnosis and treatment of cancer: Applications and challenges

F Sabir, M Zeeshan, U Laraib, M Barani, A Rahdar… - Cancers, 2021 - mdpi.com
Simple Summary DNA based and stimuli-responsive smart nano-carrier system can
efficiently deliver encapsulated cargos in response to various driving thresholds. The …

[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules

W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …

DNA Trojan Horses: Self‐Assembled Floxuridine‐Containing DNA Polyhedra for Cancer Therapy

Q Mou, Y Ma, G Pan, B Xue, D Yan… - Angewandte Chemie …, 2017 - Wiley Online Library
Based on their structural similarity to natural nucleobases, nucleoside analogue
therapeutics were integrated into DNA strands through conventional solid‐phase synthesis …