Hormonal influences in migraine—interactions of oestrogen, oxytocin and CGRP

DN Krause, K Warfvinge, KA Haanes… - Nature Reviews …, 2021 - nature.com
Migraine is ranked as the second highest cause of disability worldwide and the first among
women aged 15–49 years. Overall, the incidence of migraine is threefold higher among …

[HTML][HTML] Progesterone as an anti-inflammatory drug and immunomodulator: new aspects in hormonal regulation of the inflammation

TA Fedotcheva, NI Fedotcheva, NL Shimanovsky - Biomolecules, 2022 - mdpi.com
The specific regulation of inflammatory processes by steroid hormones has been actively
studied in recent years, especially by progesterone (P4) and progestins. The mechanisms of …

Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain

A Dedek, J Xu, LÉ Lorenzo, AG Godin… - Brain, 2022 - academic.oup.com
The prevalence and severity of many chronic pain syndromes differ across sex, and recent
studies have identified differences in immune signalling within spinal nociceptive circuits as …

Influence of TRPV1 on Thermal Nociception in Rats with Temporomandibular Joint Persistent Inflammation Evaluated by the Operant Orofacial Pain Assessment …

CRA Leite-Panissi, BB De Paula… - Journal of Pain …, 2023 - Taylor & Francis
Background temporomandibular joint (TMJ)-associated inflammation contributes to the pain
reported by patients with temporomandibular disorders (TMD). It is common for patients …

Progesterone receptor activation regulates sensory sensitivity and migraine susceptibility

S Joshi, J Williamson, S Moosa, J Kapur - The Journal of Pain, 2024 - Elsevier
Women develop chronic pain during their reproductive years more often than men, and
estrogen and progesterone regulate this susceptibility. We tested whether brain …

[HTML][HTML] Acute and preventive management of migraine during menstruation and menopause

R Ornello, E De Matteis, C Di Felice… - Journal of Clinical …, 2021 - mdpi.com
Migraine course is influenced by female reproductive milestones, including menstruation
and perimenopause; menstrual migraine (MM) represents a distinct clinical entity. Increased …

[PDF][PDF] Deep RNA-seq of male and female murine sensory neuron subtypes after nerve injury

AM Barry, N Zhao, X Yang, DL Bennett, G Baskozos - Pain, 2022 - journals.lww.com
Dorsal root ganglia (DRG) neurons have been well described for their role in driving both
acute and chronic pain. Although nerve injury is known to cause transcriptional …

[HTML][HTML] Molecular mechanisms of hormones implicated in migraine and the translational implication for transgender patients

CI Martinez, E Liktor-Busa… - Frontiers in Pain …, 2023 - ncbi.nlm.nih.gov
Migraine is a primary headache disorder recognized by the World Health Organization as
one of the most poorly understood and debilitating neurological conditions impacting global …

[HTML][HTML] Preclinical models of deep craniofacial nociception and temporomandibular disorder pain

K Okamoto, M Hasegawa, K Piriyaprasath… - … Dental Science Review, 2021 - Elsevier
Chronic pain in temporomandibular disorder (TMD) is a common health problem.
Cumulating evidence indicates that the etiology of TMD pain is complex with multifactorial …

[HTML][HTML] Correlating estrogen replacement therapy and temporomandibular disorders: a comprehensive review following PRISMA principles and cochrane handbook …

MK Alam, MA Ibrahim, MJ Almaslamani, MH Saeed… - BMC Oral Health, 2024 - Springer
Background Estrogen replacement therapy (ERT) is a common hormonal treatment for
postmenopausal women, aimed at alleviating menopausal symptoms and reducing the …