Brain structure alterations in depression: Psychoradiological evidence
FF Zhang, W Peng, JA Sweeney… - CNS neuroscience & …, 2018 - Wiley Online Library
Depression is the leading cause of disability around the world, but little is known about its
pathology. Currently, the diagnosis of depression is made based on clinical manifestations …
pathology. Currently, the diagnosis of depression is made based on clinical manifestations …
The molecular basis of drug addiction: linking epigenetic to synaptic and circuit mechanisms
EJ Nestler, C Lüscher - Neuron, 2019 - cell.com
Addiction is a disease in which, after a period of recreational use, a subset of individuals
develops compulsive use that does not stop even in light of major negative consequences …
develops compulsive use that does not stop even in light of major negative consequences …
Identification of common neural circuit disruptions in emotional processing across psychiatric disorders
LM McTeague, BM Rosenberg… - American Journal of …, 2020 - Am Psychiatric Assoc
Objective: Disrupted emotional processing is a common feature of many psychiatric
disorders. The authors investigated functional disruptions in neural circuitry underlying …
disorders. The authors investigated functional disruptions in neural circuitry underlying …
[HTML][HTML] A randomized trial directly comparing ventral capsule and anteromedial subthalamic nucleus stimulation in obsessive-compulsive disorder: clinical and …
Background Deep brain stimulation (DBS) is an emerging treatment for severe obsessive-
compulsive disorder (OCD). We compared the efficacy of ventral capsule/ventral striatal …
compulsive disorder (OCD). We compared the efficacy of ventral capsule/ventral striatal …
Value-guided remapping of sensory cortex by lateral orbitofrontal cortex
Adaptive behaviour crucially depends on flexible decision-making, which in mammals relies
on the frontal cortex, specifically the orbitofrontal cortex (OFC),,,,,,,–. How OFC encodes …
on the frontal cortex, specifically the orbitofrontal cortex (OFC),,,,,,,–. How OFC encodes …
Direct electrical stimulation of lateral orbitofrontal cortex acutely improves mood in individuals with symptoms of depression
Mood disorders cause significant morbidity and mortality, and existing therapies fail 20%–
30% of patients. Deep brain stimulation (DBS) is an emerging treatment for refractory mood …
30% of patients. Deep brain stimulation (DBS) is an emerging treatment for refractory mood …
Regional gene expression signatures are associated with sex-specific functional connectivity changes in depression
The neural substrates of depression may differ in men and women, but the underlying
mechanisms are incompletely understood. Here, we show that depression is associated with …
mechanisms are incompletely understood. Here, we show that depression is associated with …
Opportunities and limitations of genetically modified nonhuman primate models for neuroscience research
The recently developed new genome-editing technologies, such as the CRISPR/Cas
system, have opened the door for generating genetically modified nonhuman primate (NHP) …
system, have opened the door for generating genetically modified nonhuman primate (NHP) …
Subtyping schizophrenia patients based on patterns of structural brain alterations
Schizophrenia is a complex and heterogeneous syndrome. Whether quantitative imaging
biomarkers can identify discrete subgroups of patients as might be used to foster …
biomarkers can identify discrete subgroups of patients as might be used to foster …
Neurofunctional mapping of reward anticipation and outcome for major depressive disorder: a voxel-based meta-analysis
X Yang, Y Su, F Yang, Y Song, J Yan, Y Luo… - Psychological …, 2022 - cambridge.org
Aberrations in how people form expectations about rewards and how they respond to
receiving rewards are thought to underlie major depressive disorder (MDD). However, the …
receiving rewards are thought to underlie major depressive disorder (MDD). However, the …