Metabolically versatile free-living bacteria have global regulation systems that allow cells to
selectively assimilate a preferred compound among a mixture of several potential carbon …

Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …

The small nucleotide ppGpp acts as a global regulator of gene expression in bacteria.
Proteomic analysis of cells lacking ppGpp has shown that this nucleotide might affect many …

Microbial adaptation to environmental stress plays an important role in survival. It is
necessary to understand the mechanisms underlying the survival of microbes under stress …

Many regulons controlled by alternative ς factors, including ςS and ς32, are poorly induced
in cells lacking the alarmone ppGpp. We show that ppGpp is not absolutely required for the …

Pseudomonas comprises a genus of species capable of utilizing a wide range of organic
and inorganic compounds and of living under diverse environmental conditions …

The regulatory design of higher organisms is proposed to comprise a trade‐off between
activities devoted to reproduction and those devoted to cellular maintenance and repair …

Transcriptional activation of many bacterial promoters in their natural environment is not a
simple on/off decision. The expression of cognate genes is integrated in layers of iterative …

In addition to the sugar phosphotransferase system (sugar PTS) dedicated to carbohydrate
uptake, many Gram-negative bacteria possess a so-called nitrogen PTS (PTS Ntr). Although …

Throughout the 3000 million years that bacteria have been on planet Earth, they have
evolved amazing mechanisms for rapid adaptation to every imaginable type of …