The “cell kill” paradigm associated with maximum-tolerated dose (MTD) chemotherapy has
shown remarkable success in many hematological malignancies, but unfortunately has …

Fucoidan, a heparin-like sulfated polysaccharide, is rich in brown algae. It has a wide
assortment of protective activities against cancer, for example, induction of hepatocellular …

Background: The majority of lung cancer patients are diagnosed with advanced non-small
cell lung cancer (NSCLC), the bulk of which receive palliative systemic treatment with the …

Background Maintenance therapy (MT) with pemetrexed has been shown to improve overall
and progression-free survival of patients with non-squamous non-small cell lung cancer …

Current pemetrexed/platinum chemotherapy does not produce a satisfactory therapeutic
response in advanced lung cancer patients. The aim of this study was to determine whether …

Sulfated galactofucans, as the active compositions of fucoidan, were reported to exhibit
antitumor activity. In the current study, a sulfated galactofucan (SGF) from Sargassum …

Objectives Health‐related quality of life (HRQoL) is particularly important during
maintenance therapy (MT) in newly diagnosed multiple myeloma post‐transplant, when …

Introduction Preclinical data suggest quinacrine acts as an inhibitor of FACT (facilitates
chromatin transcription) complex, which may play a role in TKI (tyrosine kinase inhibitor) …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the
industrialized world. Despite significant progress in early stage disease, survival rates for …

Background Recent trials have suggested that maintenance treatments improve outcomes
for patients not progressing after first-line therapy for advanced non-small-cell lung cancer …