Turmeric, a spice that has long been recognized for its medicinal properties, has received
interest from both the medical/scientific world and from culinary enthusiasts, as it is the major …

Osteoarthritis is a leading cause of pain and disability across the world. With an aging
population its prevalence is likely to further increase. Current accepted medical treatment …

Background This study aimed to investigate the effect of bone marrow mesenchymal stem
cell (BMSC)-derived exosome injection on cartilage damage and pain relief in both in vitro …

Aim: To evaluate the efficacy of autologous adipose-derived mesenchymal stem cell
(ADMSC) therapy on pain, function and disease modification in knee osteoarthritis. Methods …

In the context of OA disease, NF-κB transcription factors can be triggered by a host of stress-
related stimuli including pro-inflammatory cytokines, excessive mechanical stress and ECM …

The reaction patterns of chondrocytes in osteoarthritis can be summarized in five
categories:(1) proliferation and cell death (apoptosis); changes in (2) synthetic activity and …

Growth plate cartilage contributes to the generation of a large variety of shapes and sizes of
skeletal elements in the mammalian system. The removal of cartilage and how this process …

Osteoarthritic cartilage destruction is caused by an imbalance between anabolic and
catabolic factors. Here, we show that hypoxia-inducible factor-2α (HIF-2α, encoded by …

INTRODUCTION: Osteoarthritis (OA) of the knee joint is caused by genetic and hormonal
factors and by inflammation, in combination with biomechanical alterations. It is …

Objective MicroRNA (miRNA) are a class of noncoding small RNAs that act as negative
regulators of gene expression. MiRNA exhibit tissue‐specific expression patterns, and …