Oxidative stress and osteoporosis

JS Kimball, JP Johnson, DWA Carlson - JBJS, 2021 - journals.lww.com
Oxidative Stress and Osteoporosis : JBJS Oxidative Stress and Osteoporosis : JBJS JBJS Journal
Case Connector Reviews JBJS.org Surgical Techniques Open Access JOPA Log in Subscribe …

Oxidative stress in the brain: basic concepts and treatment strategies in stroke

M Jelinek, M Jurajda, K Duris - Antioxidants, 2021 - mdpi.com
The production of free radicals is inevitably associated with metabolism and other enzymatic
processes. Under physiological conditions, however, free radicals are effectively eliminated …

Isothiocyanate from broccoli, sulforaphane, and its properties

A Vanduchova, P Anzenbacher… - Journal of medicinal …, 2019 - liebertpub.com
Sulforaphane is an isothiocyanate occurring in stored form as glucoraphanin in cruciferous
vegetables such as cabbage, cauliflower, and kale, and at high levels in broccoli especially …

[HTML][HTML] Sulforaphane alleviates high fat diet-induced insulin resistance via AMPK/Nrf2/GPx4 axis

Y Zhang, Q Wu, J Liu, Z Zhang, X Ma, Y Zhang… - Biomedicine & …, 2022 - Elsevier
Insulin resistance is a characteristic feature of type 2 diabetes. Sulforaphane (SFN) is a
natural antioxidant extracted from the cruciferous vegetables. Recent study reported that …

Intracerebral hemorrhage, oxidative stress, and antioxidant therapy

X Duan, Z Wen, H Shen, M Shen… - Oxidative medicine and …, 2016 - Wiley Online Library
Hemorrhagic stroke is a common and severe neurological disorder and is associated with
high rates of mortality and morbidity, especially for intracerebral hemorrhage (ICH) …

Natural compounds against doxorubicin‐induced cardiotoxicity: a review on the involvement of Nrf2/ARE signaling pathway

F Yarmohammadi, R Rezaee… - Phytotherapy Research, 2021 - Wiley Online Library
Cardiotoxicity is the main concern for long‐term use of the doxorubicin (DOX). Reactive
oxygen species (ROS) generation leads to oxidative stress that significantly contributes to …

Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders

MS Uddin, A Al Mamun, M Jakaria… - Science of the Total …, 2020 - Elsevier
Neurological disorders represent a great challenge and are the leading cause of death and
disability globally. Although numerous complicated mechanisms are involved in the …

Flavonoids activation of the transcription factor Nrf2 as a hypothesis approach for the prevention and modulation of SARS-CoV-2 infection severity

P Mendonca, KFA Soliman - Antioxidants, 2020 - mdpi.com
The Nrf2-Keap1-ARE pathway is the principal regulator of antioxidant and phase II
detoxification genes. Its activation increases the expression of antioxidant and cytoprotective …

Targeting Nrf2/Keap1 signaling pathway by bioactive natural agents: Possible therapeutic strategy to combat liver disease

R Jayasuriya, U Dhamodharan, D Ali, K Ganesan, B Xu… - Phytomedicine, 2021 - Elsevier
Background Nuclear factor erythroid 2-related factor (Nrf2), a stress-activated transcription
factor, has been documented to induce a defense mechanism against oxidative stress …

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation

Y Bai, W Cui, Y Xin, X Miao, MT Barati, C Zhang… - Journal of molecular and …, 2013 - Elsevier
This study was to investigate whether sulforaphane (SFN) can prevent diabetic
cardiomyopathy. Type 1 diabetes was induced in FVB mice by multiple intraperitoneal …