In vitro anti-trypanosomal effect of ivermectin on Trypanosoma evansi by targeting multiple metabolic pathways

S Gupta, S Vohra, K Sethi, S Gupta, BC Bera… - Tropical animal health …, 2022 - Springer
High cytotoxicity and increasing resistance reports of existing chemotherapeutic agents
against T. evansi have raised the demand for novel, potent, and high therapeutic index …

In vitro and in vivo evaluation of kinase and protease inhibitors against Trypanosoma evansi

WD Bhutia, S Gupta, R Rani, K Batra, K Sethi… - Veterinary research …, 2023 - Springer
Trypanosoma evansi is a causative agent of chronic wasting and fatal disease of livestock
and wild animals known as surra. In this study, repurposing approach based on drug target …

Gene expression study to elucidate the anti-trypanosomal activity of quinapyramine methyl sulphate (QPS)

S Gupta, S Vohra, K Sethi, S Gupta, S Kumar… - Parasitology …, 2022 - Elsevier
The kinetoplastid protozoan parasite, Trypanosoma evansi causes a fatal disease condition
known as Surra in equines throughout the globe. Disease condition being acute in nature …

Serum and stress marker indices of West African dwarf goats challenged with trypanosoma evansi and then treated with artemether-lumefantrine

AO Salifu, MH Bot, OS Olaolu, NC Uzoigwe… - Nigerian Journal of …, 2022 - njap.org.ng
The study assessed efficacy of Artemether-Lumefantrine in goats infected with Surra using
examination of parasitaemia directly and indirectly with animal inoculation using mice as a …