Phenyl-γ-valerolactones and phenylvaleric acids, the main colonic metabolites of flavan-3-ols: Synthesis, analysis, bioavailability, and bioactivity
Covering: 1958 to June 2018 Phenyl-γ-valerolactones (PVLs) and their related
phenylvaleric acids (PVAs) are the main metabolites of flavan-3-ols, the major class of …
phenylvaleric acids (PVAs) are the main metabolites of flavan-3-ols, the major class of …
Sensory nutrition and bitterness and astringency of polyphenols
Recent studies have demonstrated that the interaction of dietary constituents with taste and
olfactory receptors and nociceptors expressed in the oral cavity, nasal cavity and …
olfactory receptors and nociceptors expressed in the oral cavity, nasal cavity and …
Activation of transient receptor potential channels is involved in reactive oxygen species (ROS)-dependent regulation of blood flow by (-)-epicatechin tetramer …
T Fushimi, C Hirahata, K Hiroki, Y Fujii… - Biochemical …, 2023 - Elsevier
Intervention trials confirmed that blood flow-mediated dilatation increases significantly after
intake of astringent (-)-epicatechin (EC) oligomers (procyanidins)-rich foods, but the …
intake of astringent (-)-epicatechin (EC) oligomers (procyanidins)-rich foods, but the …
Hormetic response to B-type procyanidin ingestion involves stress-related neuromodulation via the gut-brain axis: Preclinical and clinical observations
B-type procyanidins, a series of catechin oligomers, are among the most ingested
polyphenols in the human diet. Results of meta-analyses have suggested that intake of B …
polyphenols in the human diet. Results of meta-analyses have suggested that intake of B …
Procyanidins and sensory nutrition; do procyanidins modulate homeostasis via astringent taste receptors?
Long-term intake of procyanidins has been suggested to reduce the risk of cardiovascular
disease, dementia, and sensory function decline associated with aging. However, most of …
disease, dementia, and sensory function decline associated with aging. However, most of …
Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased …
Y Nakagawa, K Ishimura, S Oya, M Kamino, Y Fujii… - PLoS …, 2018 - journals.plos.org
Objectives We previously found that elevated energy expenditure following a single oral
dose of flavan 3-ols (FL), a mixture of catechins and B type procyanidins, is caused by …
dose of flavan 3-ols (FL), a mixture of catechins and B type procyanidins, is caused by …
Acylated anthocyanins derived from purple carrot (Daucus carota L.) induce elevation of blood flow in rat cremaster arteriole
A Tsutsumi, Y Horikoshi, T Fushimi, A Saito… - Food & function, 2019 - pubs.rsc.org
Acylated anthocyanins are more stable than monomeric anthocyanins, but little is known
about their physiological effects. We evaluated the hemodynamic effects of single …
about their physiological effects. We evaluated the hemodynamic effects of single …
Effect of the consumption of hesperidin in orange juice on the transcriptomic profile of subjects with elevated blood pressure and stage 1 hypertension: A randomized …
L Pla-Pagà, RM Valls, A Pedret, L Calderón-Pérez… - Clinical Nutrition, 2021 - Elsevier
Scope Hesperidin exerts cardiovascular beneficial effects, but its mechanisms of action
remain undefined. In a previous study we demonstrated that a single dose and a 12-week …
remain undefined. In a previous study we demonstrated that a single dose and a 12-week …
Polyphenols in inner ear neurobiology, health and disease: from bench to clinics
N Osakabe, S Modafferi, ML Ontario, F Rampulla… - Medicina, 2023 - mdpi.com
There is substantial experimental and clinical interest in providing effective ways to both
prevent and slow the onset of hearing loss. Auditory hair cells, which occur along the basilar …
prevent and slow the onset of hearing loss. Auditory hair cells, which occur along the basilar …
Impact of short-term oral dose of cinnamtannin A2, an (−)-epicatechin tetramer, on spatial memory and adult hippocampal neurogenesis in mouse
Y Fujii, J Sakata, F Sato, K Onishi, Y Yamato… - Biochemical and …, 2021 - Elsevier
Recent epidemiological and intervention studies have suggested that polyphenol-rich plant
food consumption reduced the risk of cognitive decline. However, the findings were tentative …
food consumption reduced the risk of cognitive decline. However, the findings were tentative …