Synovial joints are complex structures that enable normal locomotion. Following injury, they
undergo a series of changes, including a prevalent inflammatory response. This increases …

Prevention is an attractive solution for the staggering and increasingly unmanageable
burden of osteoarthritis. Despite this, the field of osteoarthritis prevention is relatively …

The progression of osteoarthritis is associated with inflammation triggered by the enzymatic
degradation of extracellular matrix in injured cartilage. Here we show that a locally injected …

Osteoarthritis (OA) is a chronic, progressive degenerative whole joint disease that affects the
articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still …

Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of
the knee joint is important for diagnosing early disease and developing new and effective …

Osteoarthritis (OA) is one of the most common joint disorders. Evidence suggests that the
infrapatellar fat pad (IFP) is directly involved in OA pathology. However, a comparison …

Although role of the microbiome in osteoarthritis is an area of intense study, no clear
mechanism of action has been determined. Increased understanding of how the two factors …

Osteoarthritis (OA) is the most common joint disease, affecting over 300 million people world-
wide. Accumulating evidence attests to the important roles of the immune system in OA …

Secretome derived from mesenchymal stem cells (MSCs) have profound effects on tissue
regeneration, which could become the basis of future MSCs therapies. Hypoxia, as the …

Objective Stem cell therapy is increasingly used for knee osteoarthritis (KOA). We aimed to
review the evidence of autologous mesenchymal stem cell therapy on pain, function and …