Epidemiologic data indicate a significant increase in the incidence of colorectal cancer in
younger populations in the past three decades. Moreover, recent evidence also …

Background There is an increasing incidence of early-onset colorectal cancer; however, the
psychosocial impacts of this disease on younger adults have been seldom explored …

Simple Summary In this cross-sectional study, the global incidence, death, and DALY rates
of early-onset colorectal cancer (CRC) increased from 1990 to 2019, with large variations in …

Aim Neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer facilitates
tumour downstaging and complete pathological response (pCR). The goal of neoadjuvant …

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Background Colon cancer in young patients is often associated with hereditary syndromes;
however, in early-onset rectal cancer, mutations of these genes are rarely observed. The …

Although the overall incidence and mortality of colorectal cancer have declined, diagnosed
cases of young-onset colorectal cancer have increased significantly. Concerns about future …

This systematic review investigates the intersection of early-onset colorectal cancer
(EOCRC), sexual functioning, and associated quality of life (QoL), aiming to understand the …

Early‐onset colorectal cancer (EOCRC) incidence has increased in most Western countries
over the last decade, with Australia at the forefront. Recent literature has thus focused on …

The incidence of colorectal cancer among adults aged less than 50 is rising. Patients with
early-onset colorectal cancer are more likely to present with advanced disease stage with …