Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people
An East Asian–specific variant on aldehyde dehydrogenase 2 (ALDH2 rs671, G> A) is the
major genetic determinant of alcohol consumption. We performed an rs671 genotype …
major genetic determinant of alcohol consumption. We performed an rs671 genotype …
Female-biased association of NOS2-c.1823C>T (rs2297518) with co-susceptibility to metabolic syndrome and asthma
The nitric oxide (NO) pathway contributes to the pathogeneses of metabolic syndrome
(MetS) and asthma. NOS2 encodes inducible-NO synthase, which is an important enzyme of …
(MetS) and asthma. NOS2 encodes inducible-NO synthase, which is an important enzyme of …
SNPs in FAM13A and IL2RB genes are associated with FeNO in adult subjects with asthma
S Accordini, V Lando, L Calciano… - Journal of Breath …, 2023 - iopscience.iop.org
Nitric oxide has different roles in asthma as both an endogenous modulator of airway
function and a pro-inflammatory mediator. Fractional exhaled nitric oxide (FeNO) is a …
function and a pro-inflammatory mediator. Fractional exhaled nitric oxide (FeNO) is a …
Fractional exhaled nitric oxide distribution and its relevant factors in the general adult population and its healthy subpopulation
M Yamada, M Takase, K Nakaya, T Nakamura… - Journal of Allergy and …, 2024 - Elsevier
Background Measurement of fractional exhaled nitric oxide (F eno) has been used in the
diagnosis and management of asthma. Understanding the distribution of F eno in a larger …
diagnosis and management of asthma. Understanding the distribution of F eno in a larger …
Association between lung function and hypertension and home hypertension in a Japanese population: the Tohoku Medical Megabank Community-Based Cohort …
M Takase, M Yamada, T Nakamura… - Journal of …, 2023 - journals.lww.com
Background: Although several studies have shown an inverse association between lung
function and hypertension, few studies have examined the association between lung …
function and hypertension, few studies have examined the association between lung …
An observational analysis on the influence of parental allergic rhinitis, asthma and smoking on exhaled nitric oxide in offspring
Background Parental allergic diseases and smoking influence respiratory disease in the
offspring but it is not known whether they influence fractional exhaled nitric oxide (FeNO) in …
offspring but it is not known whether they influence fractional exhaled nitric oxide (FeNO) in …
Associations between birth weight and lung function in a Japanese adult population: The tohoku medical megabank community-based cohort study
T Ohe, M Yamada, A Hozawa, N Nakaya… - Respiratory …, 2023 - Elsevier
Background Birth weight, as a measure of intrauterine growth, is commonly used in
epidemiological studies and is reported to be associated with adult lung function. However …
epidemiological studies and is reported to be associated with adult lung function. However …
Carotid intima media thickness and risk factor for atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study
M Takase, N Nakaya, T Nakamura… - … of Atherosclerosis and …, 2023 - jstage.jst.go.jp
Aim: We examined the association between the carotid intima medica thickness (cIMT) and
risk factors for atherosclerosis based on the Japan Atherosclerosis Society 2022 …
risk factors for atherosclerosis based on the Japan Atherosclerosis Society 2022 …
The role of ferroptosis-related genes in airway epithelial cells of asthmatic patients based on bioinformatics
Y Zheng, J Fan, X Jiang - Medicine, 2023 - journals.lww.com
It has been reported that airway epithelial cells and ferroptosis have certain effect on
asthma. However, the action mechanism of ferroptosis-related genes in airway epithelial …
asthma. However, the action mechanism of ferroptosis-related genes in airway epithelial …
Influence of Diabetes Family History on the Associations of Combined Genetic and Lifestyle Risks with Diabetes in the Tohoku Medical Megabank Community-Based …
M Takase, N Nakaya, T Nakamura… - … of Atherosclerosis and …, 2023 - jstage.jst.go.jp
Aim: The influence of family history of diabetes, probably reflecting genetic and lifestyle
factors, on the association of combined genetic and lifestyle risks with diabetes is unknown …
factors, on the association of combined genetic and lifestyle risks with diabetes is unknown …