Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease in developed
countries. Its frequency is increasing in the general population mostly due to the widespread …

Nonalcoholic steatosis/steatohepatitis is the most common cause for abnormal liver
chemistries. Apart from metabolic syndrome, drugs may also lead to development of …

Drug-induced liver injury (DILI) is a frequent cause of liver injury and acute liver failure. We
aimed to review all hospitalized DILI cases in a tertiary Egyptian center from January 2015 …

Introduction. Amiodarone has been used for more than 5 decades for the treatment of
various tachyarrhythmias and previously for the treatment of refractory angina. There are …

肝脏是药物浓集, 转化, 代谢的主要器官. 随着全球新药的迅速市场化, 患者接触新型化合物机会
的增加, 药物性肝损伤(Drug—induced Liver Injury, DILI) 的发病呈上升趋势, 在美国和北欧国家 …

The toxicity of amiodarone Lek formulation (test formulation) was investigated after a single
intravenous (iv) administration to mice and rats. When compared to the reference item …

This cross-sectional, retrospective study was designed to evaluate the current clinical
applications and acute hepatotoxicity of intravenous amiodarone administration at a hospital …

Прием некоторых сахароснижающих лекарственных средств может быть
ассоциирован с риском развития холестатического варианта лекарственного …

Atrial fibrillation is the most commonly seen arrhythmia in the geriatric population and is
associated with increased cardiovascular morbidity and mortality. Treatment of the elderly …

Predicting drug‐induced hepatotoxicity remains a critical, yet elusive, goal in drug safety
studies and pharmaceutical development. This difficulty is, in part, a result of the often‐weak …