Purinergic signalling in the urinary tract in health and disease
G Burnstock - Purinergic signalling, 2014 - Springer
Purinergic signalling is involved in a number of physiological and pathophysiological
activities in the lower urinary tract. In the bladder of laboratory animals there is …
activities in the lower urinary tract. In the bladder of laboratory animals there is …
Changes in afferent activity after spinal cord injury
WC de Groat, N Yoshimura - Neurourology and Urodynamics …, 2010 - Wiley Online Library
Aims To summarize the changes that occur in the properties of bladder afferent neurons
following spinal cord injury. Methods Literature review of anatomical, immunohistochemical …
following spinal cord injury. Methods Literature review of anatomical, immunohistochemical …
Plasticity in reflex pathways to the lower urinary tract following spinal cord injury
WC de Groat, N Yoshimura - Experimental neurology, 2012 - Elsevier
The lower urinary tract has two main functions, storage and periodic expulsion of urine, that
are regulated by a complex neural control system in the brain and lumbosacral spinal cord …
are regulated by a complex neural control system in the brain and lumbosacral spinal cord …
Neuroimmune system as a driving force for plasticity following CNS injury
ML O'Reilly, VJ Tom - Frontiers in cellular neuroscience, 2020 - frontiersin.org
Following an injury to the central nervous system (CNS), spontaneous plasticity is observed
throughout the neuraxis and affects multiple key circuits. Much of this spontaneous plasticity …
throughout the neuraxis and affects multiple key circuits. Much of this spontaneous plasticity …
Assessing neurogenic lower urinary tract dysfunction after spinal cord injury: Animal models in preclinical neuro-urology research
Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …
Spinal cord injury and bladder dysfunction: new ideas about an old problem
CD Cruz, F Cruz - The scientific world journal, 2011 - Wiley Online Library
Control of the lower urinary tract (LUT) requires complex neuronal circuits that involve
elements located at the peripheral nervous system and at different levels of the central …
elements located at the peripheral nervous system and at different levels of the central …
A biophysically detailed computational model of urinary bladder small DRG neuron soma
D Mandge, R Manchanda - PLoS computational biology, 2018 - journals.plos.org
Bladder small DRG neurons, which are putative nociceptors pivotal to urinary bladder
function, express more than a dozen different ionic membrane mechanisms: ion channels …
function, express more than a dozen different ionic membrane mechanisms: ion channels …
[HTML][HTML] Slow development of bladder malfunction parallels spinal cord fiber sprouting and interneurons' loss after spinal cord transection
AM Sartori, AS Hofer, MI Scheuber, R Rust… - Experimental …, 2022 - Elsevier
Neurogenic lower urinary tract dysfunction typically develops after spinal cord injury. We
investigated the time course and the anatomical changes in the spinal cord that may be …
investigated the time course and the anatomical changes in the spinal cord that may be …
Sprouting of substance P-expressing primary afferent central terminals and spinal micturition reflex NK1 receptor dependence after spinal cord injury
X Zhang, KL Douglas, H Jin, BM Eldaif… - American Journal …, 2008 - journals.physiology.org
The primary afferent neurotransmitter triggering the spinal micturition reflex after complete
spinal cord injury (SCI) in the rat is unknown. Substance P detected immunohistochemically …
spinal cord injury (SCI) in the rat is unknown. Substance P detected immunohistochemically …
Chronic chemogenetic inhibition of TRPV1 bladder afferent promotes micturition recovery post SCI
L Ma, C Zhu, YF Wei, JY Zhou, M Chen, X Zhang… - Experimental …, 2024 - Elsevier
Spinal cord injury often results in chronic loss of micturition control, which is featured by
bladder hyperreflexia and detrusor sphincter dyssynergia. Previous studies showed that …
bladder hyperreflexia and detrusor sphincter dyssynergia. Previous studies showed that …