Purinergic signalling is involved in a number of physiological and pathophysiological
activities in the lower urinary tract. In the bladder of laboratory animals there is …

Aims To summarize the changes that occur in the properties of bladder afferent neurons
following spinal cord injury. Methods Literature review of anatomical, immunohistochemical …

The lower urinary tract has two main functions, storage and periodic expulsion of urine, that
are regulated by a complex neural control system in the brain and lumbosacral spinal cord …

Following an injury to the central nervous system (CNS), spontaneous plasticity is observed
throughout the neuraxis and affects multiple key circuits. Much of this spontaneous plasticity …

Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …

Control of the lower urinary tract (LUT) requires complex neuronal circuits that involve
elements located at the peripheral nervous system and at different levels of the central …

Bladder small DRG neurons, which are putative nociceptors pivotal to urinary bladder
function, express more than a dozen different ionic membrane mechanisms: ion channels …

Neurogenic lower urinary tract dysfunction typically develops after spinal cord injury. We
investigated the time course and the anatomical changes in the spinal cord that may be …

The primary afferent neurotransmitter triggering the spinal micturition reflex after complete
spinal cord injury (SCI) in the rat is unknown. Substance P detected immunohistochemically …

Spinal cord injury often results in chronic loss of micturition control, which is featured by
bladder hyperreflexia and detrusor sphincter dyssynergia. Previous studies showed that …