Proksee: in-depth characterization and visualization of bacterial genomes

JR Grant, E Enns, E Marinier, A Mandal… - Nucleic acids …, 2023 - academic.oup.com
Abstract Proksee (https://proksee. ca) provides users with a powerful, easy-to-use, and
feature-rich system for assembling, annotating, analysing, and visualizing bacterial …

TMPRSS2 is a functional receptor for human coronavirus HKU1

N Saunders, I Fernandez, C Planchais, V Michel… - Nature, 2023 - nature.com
Four endemic seasonal human coronaviruses causing common colds circulate worldwide:
HKU1, 229E, NL63 and OC43 (ref.). After binding to cellular receptors, coronavirus spike …

[HTML][HTML] Phage susceptibility determinants of the opportunistic pathogen Staphylococcus epidermidis

C Beck, J Krusche, AMA Elsherbini, X Du… - Current Opinion in …, 2024 - Elsevier
Highlights•Temperate phages of Staphylococcus epidermidis facilitate horizontal gene
transfer.•Wall teichoic acid glycosylation determines binding of S. epidermidis phages.•The …

Biosynthesis and function of 7-deazaguanine derivatives in bacteria and phages

V de Crécy-Lagard, G Hutinet… - Microbiology and …, 2024 - Am Soc Microbiol
Deazaguanine modifications play multifaceted roles in the molecular biology of DNA and
tRNA, shaping diverse yet essential biological processes, including the nuanced fine-tuning …

Guidelines for public database submission of uncultivated virus genome sequences for taxonomic classification

EM Adriaenssens, S Roux, JR Brister… - Nature …, 2023 - nature.com
RNA sequencing approaches, including metagenomics, has led to the discovery of a
multitude of uncultivated virus genome sequences 1–12. These sequences improve our …

[HTML][HTML] Highly pathogenic avian influenza a (H5N1) clade 2.3. 4.4 b virus in wild birds, Chile

N Ariyama, C Pardo-Roa, G Muñoz… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
In December 2022, highly pathogenic avian influenza A (H5N1) clade 2.3. 4.4 b virus
emerged in Chile. We detected H5N1 virus in 93 samples and obtained 9 whole-genome …

[HTML][HTML] Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle

X Ding, C Robbe-Masselot, X Fu, R Léonard… - Nature …, 2023 - nature.com
Staphylococcus aureus is a predominant cause of chronic lung infections. While the airway
environment is rich in highly sialylated mucins, the interaction of S. aureus with sialic acid is …

[HTML][HTML] An atlas of continuous adaptive evolution in endemic human viruses

KE Kistler, T Bedford - Cell host & microbe, 2023 - cell.com
Through antigenic evolution, viruses such as seasonal influenza evade recognition by
neutralizing antibodies. This means that a person with antibodies well tuned to an initial …

[HTML][HTML] Whole Genome Sequencing for Studying Helicobacter pylori Antimicrobial Resistance

B Fernández-Caso, A Miqueleiz, T Alarcón - Antibiotics, 2023 - mdpi.com
Antibiotic resistance (AMR) is an alarming concern worldwide and Helicobacter pylori, one
of the most prevalent bacteria, is not an exception. With antibiotics being its primary therapy …

[HTML][HTML] Cross-species transmission and PB2 mammalian adaptations of highly pathogenic avian influenza A/H5N1 viruses in Chile

C Pardo-Roa, MI Nelson, N Ariyama, C Aguayo… - bioRxiv, 2023 - ncbi.nlm.nih.gov
H5N1 highly pathogenic avian influenza viruses (HPAIV) emerged in wild birds in Chile in
December 2022 and spilled over into poultry, marine mammals, and one human. Between …