[HTML][HTML] Effectiveness of protease inhibitor monotherapy versus combination antiretroviral maintenance therapy: a meta-analysis

S Mathis, B Khanlari, F Pulido, M Schechter… - PloS one, 2011 - journals.plos.org
Background The unparalleled success of combination antiretroviral therapy (cART) is based
on the combination of three drugs from two classes. There is insufficient evidence whether …

HIV infection and advanced age: emerging epidemiological, clinical, and management issues

R Manfredi - Ageing research reviews, 2004 - Elsevier
While the mean age of HIV/AIDS patients at first diagnosis is progressively rising, no
updated epidemiological estimates, controlled clinical data, and randomized therapeutic …

Should resistance testing be performed for treatment-naive HIV-infected patients? A cost-effectiveness analysis

PE Sax, R Islam, RP Walensky, E Losina… - Clinical infectious …, 2005 - academic.oup.com
Methods. We utilized a state-transition model of HIV disease to project life expectancy, costs,
and cost-effectiveness in a hypothetical cohort of antiretroviral-naive patients with chronic …

Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection

M Van der Valk, EH Gisolf, P Reiss, F Wit, A Japour… - Aids, 2001 - journals.lww.com
Background Changes in body fat distribution are an adverse effect of therapy with HIV
protease inhibitors (PI). It has been suggested that nucleoside analogue reverse …

Combination of protease inhibitors for the treatment of HIV-1-infected patients: a review of pharmacokinetics and clinical experience

RPG Van Heeswijk, AI Veldkamp, JW Mulder… - Antiviral …, 2002 - journals.sagepub.com
The use of highly active antiretroviral therapy, the combination of at least three different
antiretroviral drugs for the treatment of HIV-1 infection, has greatly improved the prognosis …

Risk Factors for Hepatotoxicity in HIV-1—Infected Patients Receiving Ritonavir and Saquinavir with or without Stavudine

EH Gisolf, C Dreezen, SA Danner… - Clinical infectious …, 2000 - academic.oup.com
Liver enzyme elevation (LEE) is commonly observed after combination antiretroviral therapy
(ARVT) for HIV infection is begun. Potential risk factors for LEE after treatment with ritonavir …

[HTML][HTML] HIV disease and advanced age: an increasing therapeutic challenge

R Manfredi - Drugs & aging, 2002 - Springer
The mean age of patients at both first HIV detection and AIDS diagnosis is progressively
rising over time. However, reliable epidemiological estimates, clinical data or controlled …

Determinants of recurrent toxicity-driven switches of highly active antiretroviral therapy. The ATHENA cohort

JP Dieleman, M Jambroes, IC Gyssens… - Aids, 2002 - journals.lww.com
Background Toxicity is the most important reason for premature switching of highly active
antiretroviral therapy (HAART). In order to optimize the benefit–risk ratio of HAART …

Long-term quality of life outcomes in three antiretroviral treatment strategies for HIV-1 infection

PT Nieuwkerk, EH Gisolf, MHE Reijers, JMA Lange… - Aids, 2001 - journals.lww.com
Objective To compare changes in quality of life (QoL) over 96 weeks in patients enrolled in a
triple-therapy protocol, a treatment-intensification protocol, or an induction-maintenance …

Increased lipodystrophy is associated with increased exposure to highly active antiretroviral therapy in HIV-infected children

A Viganò, S Mora, C Testolin, S Beccio… - JAIDS Journal of …, 2003 - journals.lww.com
Objective To assess body composition changes in HIV-infected children receiving highly
active antiretroviral therapy (HAART). Methods Thirty-seven HIV-positive children were …