Surgical tumor-derived personalized photothermal vaccine formulation for cancer immunotherapy

X Ye, X Liang, Q Chen, Q Miao, X Chen, X Zhang… - ACS …, 2019 - ACS Publications
Personalized cancer vaccines show great potential in cancer immunotherapy by inducing an
effective and durable antitumor response. However, the limitation of neoantigen …

Neutrophil‐based drug delivery systems

D Chu, X Dong, X Shi, C Zhang, Z Wang - Advanced materials, 2018 - Wiley Online Library
White blood cells (WBCs) are a major component of immunity in response to pathogen
invasion. Neutrophils are the most abundant WBCs in humans, playing a central role in …

Unconventional T cell targets for cancer immunotherapy

DI Godfrey, J Le Nours, DM Andrews, AP Uldrich… - Immunity, 2018 - cell.com
Most studies on the immunotherapeutic potential of T cells have focused on CD8 and CD4 T
cells that recognize peptide antigens (Ag) presented by polymorphic major histocompatibility …

Monalizumab: inhibiting the novel immune checkpoint NKG2A

T Van Hall, P André, A Horowitz, DF Ruan… - … for immunotherapy of …, 2019 - Springer
The implementation of immune checkpoint inhibitors to the oncology clinic signified a new
era in cancer treatment. After the first indication of melanoma, an increasing list of additional …

Immunotherapy and Prevention of Cancer by Nanovaccines Loaded with Whole‐Cell Components of Tumor Tissues or Cells

L Ma, L Diao, Z Peng, Y Jia, H Xie, B Li, J Ma… - Advanced …, 2021 - Wiley Online Library
Tumor tissues/cells are the best sources of antigens to prepare cancer vaccines. However,
due to the difficulty of solubilization and delivery of water‐insoluble antigens in tumor …

Biointerfacing and applications of cell membrane-coated nanoparticles

AV Kroll, RH Fang, L Zhang - Bioconjugate chemistry, 2017 - ACS Publications
The cell membrane-coated nanoparticle is a biomimetic platform consisting of a
nanoparticulate core coated with membrane derived from a cell, such as a red blood cell …

Immunomodulation of the tumor microenvironment: turn foe into friend

H Locy, S De Mey, W De Mey, M De Ridder… - Frontiers in …, 2018 - frontiersin.org
Immunotherapy, where the patient's own immune system is exploited to eliminate tumor
cells, has become one of the most prominent new cancer treatment options in the last …

Human papillomavirus in the setting of immunodeficiency: Pathogenesis and the emergence of next-generation therapies to reduce the high associated cancer risk

RV Hewavisenti, J Arena, CL Ahlenstiel… - Frontiers in …, 2023 - frontiersin.org
Human papillomavirus (HPV), a common sexually transmitted virus infecting mucosal or
cutaneous stratified epithelia, is implicated in the rising of associated cancers worldwide …

A minimalist binary vaccine carrier for personalized postoperative cancer vaccine therapy

J Zhao, Y Xu, S Ma, Y Wang, Z Huang, H Qu… - Advanced …, 2022 - Wiley Online Library
In recent years, significant evolutions have been made in applying nanotechnologies for
prophylactic and therapeutic cancer vaccine design. However, the clinical translation of …

Harnessing the immune system against cancer: current immunotherapy approaches and therapeutic targets

AR Kumar, AR Devan, B Nair, BS Vinod… - Molecular biology …, 2021 - Springer
Cancer immunotherapy is a rapidly evolving concept that has been given the tag" fifth pillar"
of cancer therapy while radiation therapy, chemotherapy, surgery and targeted therapy …