Model-based glycaemic control in critical care—A review of the state of the possible
Hyperglycaemia is prevalent in critical care, as patients experience stress-induced
hyperglycaemia, even with no history of diabetes. Hyperglycaemia in critical care is not …
hyperglycaemia, even with no history of diabetes. Hyperglycaemia in critical care is not …
Modeling insulin action for development of a closed-loop artificial pancreas
GM Steil, B Clark, S Kanderian… - Diabetes technology & …, 2005 - liebertpub.com
Three models of glucose homeostasis are compared in terms of their steady-state dose–
response characteristics, how they characterize glucose distribution kinetics, and how they …
response characteristics, how they characterize glucose distribution kinetics, and how they …
A blood glucose control framework based on reinforcement learning with safety and interpretability: In silico validation
Controlling blood glucose levels in diabetic patients is important for managing their health
and quality of life. Several algorithms based on model predictive control and reinforcement …
and quality of life. Several algorithms based on model predictive control and reinforcement …
Intracellullar peptides as putative natural regulators of protein interactions
ES Ferro, S Hyslop, ACM Camargo - Journal of neurochemistry, 2004 - Wiley Online Library
Extralysosomal proteolysis by multicatalytic complexes such as the 26S proteasome
produces large amounts of peptides in the cytosol, mitochondria and nuclei of eukaryotic …
produces large amounts of peptides in the cytosol, mitochondria and nuclei of eukaryotic …
Undermodeling affects minimal model indexes: insights from a two-compartment model
The classic (hereafter cold) and the labeled (hereafter hot) minimal models are powerful
tools to investigate glucose metabolism. The cold model provides, from intravenous glucose …
tools to investigate glucose metabolism. The cold model provides, from intravenous glucose …
[HTML][HTML] A review of closed-loop algorithms for glycemic control in the treatment of type 1 diabetes
J El Youssef, J Castle, WK Ward - Algorithms, 2009 - mdpi.com
With the discovery of insulin came a deeper understanding of therapeutic options for one of
the most devastating chronic diseases of the modern era, diabetes mellitus. The use of …
the most devastating chronic diseases of the modern era, diabetes mellitus. The use of …
Measurement of selective effect of insulin on glucose disposal from labeled glucose oral test minimal model
The oral glucose minimal model (OMM) measures insulin sensitivity (SI) and the glucose
rate of appearance (Ra) of ingested glucose in the presence of physiological changes of …
rate of appearance (Ra) of ingested glucose in the presence of physiological changes of …
Simulation models for in silico testing of closed-loop glucose controllers in type 1 diabetes
ME Wilinska, R Hovorka - Drug Discovery Today: Disease Models, 2008 - Elsevier
Models of glucose regulation have a longstanding history dating back 40 years. Various
modelling approaches have been adopted providing models of varied complexity ranging …
modelling approaches have been adopted providing models of varied complexity ranging …
Modeling of 24‐hour glucose and insulin profiles of patients with type 2 diabetes
PM Jauslin, N Frey, MO Karlsson - The Journal of Clinical …, 2011 - Wiley Online Library
A model able to simultaneously characterize and simulate 24‐hour glucose and insulin
profiles following multiple meal tests was developed, extending an integrated glucose …
profiles following multiple meal tests was developed, extending an integrated glucose …
Mixed meal simulation model of glucose-insulin system
C Dalla Man, RA Rizza, C Cobelli - … International Conference of …, 2006 - ieeexplore.ieee.org
A simulation model of the glucose-insulin system in the postprandial state can be useful for
studying the pathophysiology of diabetes. Here we present a new simulation model which …
studying the pathophysiology of diabetes. Here we present a new simulation model which …