Most nanozymes in development for medical applications only exhibit single‐enzyme‐like
activity, and are thus limited by insufficient catalytic activity and dysfunctionality in complex …

Parkinson's Disease (PD) is characterized by the progressive loss of dopaminergic neurons
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …

Vascular aging contributes to adverse changes in organ function and is a significant
indicator of major cardiac events. Endothelial cells (ECs) participate in aging-provoked …

Renal ischemia/reperfusion (I/R) injury contributes to the development of acute kidney injury
(AKI). Kidney is the second organ rich in mitochondrial content next to the heart …

After the discovery of cisplatin, many metal compounds were investigated for the therapy of
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …

Introduction Matrine (MT), an ingredient extracted from the Chinese herb Sophora
flavescens, can result in nephrotoxicity because of long-term exposure. However, the …

Reactive oxygen species (ROS)‐induced mitophagy is associated with a variety of diseases.
Therefore, visualizing and modulating the process of ROS‐induced mitophagy is essential …

Cardiovascular disease (CVD) is a group of systemic disorders threatening human health
with complex pathogenesis, among which mitochondrial energy metabolism reprogramming …

Abstract Tris (1, 3-dichloro-2-propyl) phosphate (TDCPP) has neurotoxicity, but its
mechanism remains unclear. Evidence recently showed that ferroptosis might be associated …

5-Fluorouracil (5-FU) is a chemotherapy drug widely used to treat a range of cancer types,
despite the recurrence of adverse reactions. Therefore, information on its side effects when …