Decades of research have identified genetic factors and biochemical pathways involved in
neurodegenerative diseases (NDDs). We present evidence for the following eight hallmarks …

Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Ischemic stroke represents a significant danger to human beings, especially the elderly.
Interventions are only available to remove the clot, and the mechanism of neuronal death …

Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

Ischemic stroke is one of the significant causes of morbidity and mortality, affecting millions
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …

Stroke constitutes the second leading cause of death and a major cause of disability
worldwide. Stroke is normally classified as either ischemic or hemorrhagic stroke (HS) …

Ischemic stroke refers to the disorder of blood supply of local brain tissue caused by various
reasons. It has high morbidity and mortality worldwide. Astrocytes are the most abundant …

Stroke is the leading cause of adult disability and mortality in most developing and
developed countries. The current best practices for patients with acute ischemic stroke …