Preparing (metalla) carboranes for nanomedicine

M Gozzi, B Schwarze, E Hey‐Hawkins - ChemMedChem, 2021 - Wiley Online Library
Abstract “There's plenty of room at the bottom”(Richard Feynman, 1959): an invitation for
(metalla) carboranes to enter the (new) field of nanomedicine. For two decades, the number …

High-performance thin-layer chromatography-immunostaining as a technique for the characterization of whey protein enrichment in edam cheese

M Treblin, T von Oesen, J Lüneburg… - Foods, 2022 - mdpi.com
Whey protein-enriched cheese can be produced by means of a high-temperature treatment
of a part of the cheese milk. In this way, the nutritional quality of the resulting cheeses can be …

Transfer of blocker-based qPCR reactions for DNA methylation analysis into a microfluidic LoC system using thermal modeling

J Kärcher, B Schulze, A Dörr, S Tierling, J Walter - Biomicrofluidics, 2022 - pubs.aip.org
Changes in the DNA methylation landscape are associated with many diseases like cancer.
Therefore, DNA methylation analysis is of great interest for molecular diagnostics and can …

Spin Labeling of RNA Using “Click” Chemistry for Coarse-grained Structure Determination via Pulsed Electron-electron Double Resonance Spectroscopy

MF Vicino, T Hett, O Schiemann - Bio-protocol, 2021 - bio-protocol.org
Understanding the function of oligonucleotides on a molecular level requires methods for
studying their structure, conformational changes, and internal dynamics. Various biophysical …

[PDF][PDF] The activity and isoforms of NADP-malic enzyme in Nicotiana benthamiana plants under biotic stress

V Doubnerová, A Jiraskova, M Janoskova… - General Physiology …, 2007 - researchgate.net
The activity and presence of isoforms of NADP-dependent malic enzyme (NADP-ME, EC
1.1. 1.40) were studied in non-transgenic and transgenic Nicotiana benthamiana plants …

Particle Analytics: Comparative Approaches for Analysis of Viral Vectors

I Skaripa-Koukelli, A Raducanu… - … Development for Virus …, 2023 - Springer
In recent years, recombinant adeno-associated virus (rAAV) mediated gene therapy
approaches have proved the tremendous potential ascribed to them by means of providing …

Mass spectrometric detection and characterization of covalent reaction products between the chemical warfare agent sulfur mustard and human serum albumin and …

M Siegert - 2023 - edoc.hu-berlin.de
Sulfur mustard (SM) is a banned chemical warfare agent. After incorporation, SM may cause
tremendous symptoms. On the molecular level, SM reacts with DNA and proteins. These …

[PDF][PDF] Low-cost Spectroscopy: Experiments in Various Spectral Ranges

P Gräb, E Geidel, HC Schmitt - World Journal …, 2021 - article.journalofchemicaleducation …
Teaching the basic principles of molecular spectroscopic techniques on an experimental
basis is often a particular challenge due to the relatively high cost of the required …

Evaluation of sample preparation methods for protein analysis of liver organoids

L Midtøy - 2023 - duo.uio.no
For mass spectrometry (MS)-based proteomics, different sample preparation methods were
evaluated for limited cell samples (10 000-200 000 cells), and the optimized method was …

Evaluation of Bottom-Up and Middle-Up Liquid Chromatography Mass Spectrometry Methods for Forced Degradation Studies applied in Biosimilar Development

Y Dyck - 2023 - refubium.fu-berlin.de
The characterization of post-translational modifications (PTMs) is an important part of
therapeutic monoclonal antibody (mAb) quality assurance. Modification by oxidation is one …