The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …

Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Interoception, the sense of the body's internal physiological state, underpins homeostatic
reflexes, motivational states, and sensations contributing to emotional experiences. The …

The prevalence of obesity is a major cause of many chronic metabolic disorders, including
type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), and cancer. Insulin …

Interactions between the brain and distinct adipose depots have a key role in maintaining
energy balance, thereby promoting survival in response to metabolic challenges such as …

The hypothalamus, which regulates fundamental aspects of physiological homeostasis and
behavior, is a brain region that exhibits highly conserved anatomy across vertebrate …

Neurodegenerative diseases (NDDs) are disorders characterized by progressive
deterioration of brain structure and function. Selective neuronal populations are affected …

Astrocytes support neuronal function by providing essential structural and nutritional
support, neurotransmitter trafficking and recycling and may also contribute to brain …

Oxytocin neurones in the hypothalamus are activated by stressful stimuli and food intake.
The oxytocin receptor is located in various brain regions, including the sensory information …

Introducción. En mamíferos, el control de la temperatura corporal es vital. El estado de
consciencia y control motor en humanos, ocurren a una temperatura de 37 C y las …