Over the past few decades, there has been a notable increase in the global burden of
central nervous system (CNS) diseases. Despite advances in technology and therapeutic …

Background: In recent years, extracellular vesicles have been recognized as important
mediators of intercellular communication through the transfer of active biomolecules …

Background Stem cell-derived extracellular vesicles (EVs) are an emerging class of
therapeutics with excellent biocompatibility, bioactivity and pro-regenerative capacity. One of …

In recent years, tremendous progress has been made in understanding the roles of
extracellular vesicles (EVs) in cancer. Thanks to advancements in molecular biology, it has …

Exosomes are small nanoscale vesicles with a double-layered lipid membrane structure
secreted by cells, and almost all types of cells can secrete exosomes. Exosomes carry a …

The bone marrow (BM) niche is the spatial structure within the intra-trabecular spaces of
spongious bones and of the cavity of long bones where adult haematopoietic stem cells …

Background Cardiac fibrosis is one of the top killers among fibrotic diseases and continues
to be a global unaddressed health problem. The lack of effective treatment combined with …

The reduction in the quantity and quality of oocytes is the major factor affecting fertility in
women with advanced age, who tend to experience delayed childbearing and declined …

Aims Extracellular vesicles (EVs) are nanoparticles secreted by all cells, enriched in
proteins, lipids, and nucleic acids related to cell-to-cell communication and vital components …

A new therapeutic approach using cell‐derived nanovesicles (cdNVs) is offered here to
overcome the lack of effective treatments for liver fibrosis, a reversible chronic liver disease …