Current analytical methods for determination of glucosinolates in vegetables and human tissues

AY Almushayti, K Brandt, MA Carroll… - Journal of Chromatography …, 2021 - Elsevier
Numerous epidemiological studies have indicated the potential effects of glucosinolates and
their metabolites against cancer as well as other non-communicable diseases, such as …

[HTML][HTML] The Role of Glucosinolate Hydrolysis Products from Brassica Vegetable Consumption in Inducing Antioxidant Activity and Reducing Cancer Incidence

TM Becker, JA Juvik - Diseases, 2016 - mdpi.com
The bioactivity of glucosinolates (GSs), and more specifically their hydrolysis products
(GSHPs), has been well documented. These secondary metabolites evolved in the order …

[HTML][HTML] Guided Metabolic Detoxification program supports phase II detoxification enzymes and antioxidant balance in healthy participants

C Panda, S Komarnytsky, MN Fleming, C Marsh… - Nutrients, 2023 - mdpi.com
Adequate antioxidant supply is essential for maintaining metabolic homeostasis and
reducing oxidative stress during detoxification. The emerging evidence suggests that certain …

Sulforaphane protects against ethanol‐induced oxidative stress and apoptosis in neural crest cells by the induction of N rf2‐mediated antioxidant response

X Chen, J Liu, SY Chen - British journal of pharmacology, 2013 - Wiley Online Library
Background and Purpose Nuclear factor erythroid 2‐related factor (N rf2) is a transcription
factor that up‐regulates a diverse array of antioxidant genes and protects cells from …

[HTML][HTML] Sulforaphane protects against brain diseases: roles of cytoprotective enzymes

Y Sun, T Yang, L Mao, F Zhang - Austin journal of cerebrovascular …, 2017 - ncbi.nlm.nih.gov
Sulforaphane (SFN) is a kind of isothiocyanate derived from broccoli and other cruciferous
vegetables. Because of its roles of antioxidant, anti-inflammatory, and anti-tumor through …

[PDF][PDF] Potential health benefits of sulforaphane: a review of the experimental, clinical and epidemiological evidences and underlying mechanisms

F Elbarbry, N Elrody - J Med Plants Res, 2011 - academicjournals.org
Extensive epidemiological evidence and animal experimental studies suggest that
cruciferous vegetables may prevent or delay various inflammatory disorders, including …

[HTML][HTML] Protective mechanism of sulforaphane on cadmium-induced sertoli cell injury in mice testis via Nrf2/ARE signaling pathway

SH Yang, LH Yu, L Li, Y Guo, Y Zhang, M Long, P Li… - Molecules, 2018 - mdpi.com
The present study evaluated the mechanism underlying the protective effect of sulforaphane
(SFN) on cadmium (Cd)-induced Sertoli cell (TM4 cells) injury in mice. The apoptosis rate of …

Sweet Chestnut (Castanea sativa Mill.) Bark Extract: Cardiovascular Activity and Myocyte Protection against Oxidative Damage

A Chiarini, M Micucci, M Malaguti… - Oxidative Medicine …, 2013 - Wiley Online Library
This work was aimed at evaluating the cardioprotective effects of Castanea sativa Mill.(CSM)
bark extract characterized in its phenolic composition by HPLC‐DAD‐MS analysis. The …

[PDF][PDF] Keap1-Nrf2/ARE 信号通路的抗氧化应激作用及其调控机制

胡流芳, 王迎, 任汝静, 霍海如, 孙建辉… - 国际药学研究 …, 2016 - genetechchina.com
Kelch 样环氧氯丙烷相关蛋白. 1 (Keap1). 核因子E2 相关因子2 (Nrf2)/~ 氧化反应元件(ARE)
信号通路是细胞氧化应激反应中的关键通路, 其调控的下游Ⅱ 相代谢酶和抗氧化蛋白/酶在细胞 …

[图书][B] Activation and detoxification enzymes: functions and implications

CH Chen - 2012 - Springer
Humans are exposed to foreign compounds such as drugs, household products and
environmental chemicals by swallowing or breathing. Also, food is considered a foreign …