17β-Estradiol enhances sulforaphane cardioprotection against oxidative stress

C Angeloni, G Teti, MC Barbalace, M Malaguti… - The Journal of …, 2017 - Elsevier
The lower incidence of ischemic heart disease in female with respect to male gender
suggests the possibility that female sex hormones could have specific effects in …

Sulforaphane modulates AQP8‐linked redox signalling in leukemia cells

C Prata, C Facchini, E Leoncini, M Lenzi… - Oxidative medicine …, 2018 - Wiley Online Library
Sulforaphane, a biologically active isothiocyanate compound extracted from cruciferous
vegetables, has been shown to exert cytotoxic effects on many human cancer cells …

Lagerstroemia speciosa L. Attenuates Apoptosis in Isoproterenol-Induced Cardiotoxic Mice by Inhibiting Oxidative Stress: Possible Role of Nrf2/HO-1

BD Sahu, M Kuncha, SS Rachamalla, R Sistla - Cardiovascular toxicology, 2015 - Springer
Myocardial oxidative stress leading to apoptosis and remodeling is the major consequence
of ischemic heart disease. In the present study, we investigated the effect of Lagerstroemia …

Health functionality of organosulfides: a review

F Frankel, M Priven, E Richard… - … Journal of Food …, 2016 - Taylor & Francis
Phytonutrients are chemicals that are derived from plants and aid in both human health as
well as the prevention of chronic disease. One type of phytonutrient classification is …

Novel targets of sulforaphane in primary cardiomyocytes identified by proteomic analysis

C Angeloni, S Turroni, L Bianchi, D Fabbri, E Motori… - PLoS …, 2013 - journals.plos.org
Cardiovascular diseases represent the main cause of mortality in the industrialized world
and the identification of effective preventive strategies is of fundamental importance …

Sulforaphane Exposure Prevents Cadmium-Induced Toxicity and Mitochondrial Dysfunction in the Nematode Caenorhabditis elegans by Regulating the Insulin …

EY Hernández-Cruz, OE Aparicio-Trejo… - Antioxidants, 2024 - mdpi.com
Cadmium (Cd) is a heavy metal that is highly toxic to humans and animals. Its adverse
effects have been widely associated with mitochondrial alterations. However, there are not …

[HTML][HTML] Sulforaphane effects on oxidative stress parameters in culture of adult cardiomyocytes

GB Corssac, C Campos-Carraro, A Hickmann… - Biomedicine & …, 2018 - Elsevier
The aim of this study was to analyse the effect of sulforaphane (SFN) in cultures of adult
cardiomyocytes, evaluating oxidative stress at different times. Cells were isolated, cultured …

Differential mechanistic investigation of protective effects from imperatorin and sec-O-glucosylhamaudol against arsenic trioxide-induced cytotoxicity in vitro

L Hu, J Sun, H Li, L Wang, Y Wei, Y Wang, Y Zhu… - Toxicology in Vitro, 2016 - Elsevier
Background and purpose The clinical use of arsenic trioxide (As 2 O 3) for treating acute
promyelocytic leukemia (APL) is limited due to its severe cardiotoxicity. The possible …

Age‐related changes in cellular protection, purification, and inflammation‐related gene expression: role of dietary phytonutrients

A Mastaloudis, SM Wood - Annals of the New York Academy of …, 2012 - Wiley Online Library
Oxidative injury and inflammation are intimately involved in the aging process and the
development of age‐related diseases. To date, most nutritional antiaging strategies have …

Sulforaphane attenuates homocysteine-induced endoplasmic reticulum stress through Nrf-2-driven enzymes in immortalized human hepatocytes

C He, B Li, W Song, Z Ding, S Wang… - Journal of agricultural …, 2014 - ACS Publications
In the present study, we investigated the potential efficacy of cruciferous vegetable-derived
sulforaphane (SFN) in improving homocysteine (HCY)-stressed cells. After human …