[HTML][HTML] High-content CRISPR screening
CRISPR screens are a powerful source of biological discovery, enabling the unbiased
interrogation of gene function in a wide range of applications and species. In pooled …
interrogation of gene function in a wide range of applications and species. In pooled …
[HTML][HTML] Review of COVID-19 testing and diagnostic methods
O Filchakova, D Dossym, A Ilyas, T Kuanysheva… - Talanta, 2022 - Elsevier
More than six billion tests for COVID-19 has been already performed in the world. The
testing for SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) virus and …
testing for SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) virus and …
Mechanism and applications of CRISPR/Cas-9-mediated genome editing
M Asmamaw, B Zawdie - Biologics: targets and therapy, 2021 - Taylor & Francis
Clustered regularly interspaced short palindromic repeat (CRISPR) and their associated
protein (Cas-9) is the most effective, efficient, and accurate method of genome editing tool in …
protein (Cas-9) is the most effective, efficient, and accurate method of genome editing tool in …
CRISPR/Cas-powered nanobiosensors for diagnostics
QA Phan, LB Truong, D Medina-Cruz, C Dincer… - Biosensors and …, 2022 - Elsevier
CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …
Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections
Y Wu, D Battalapalli, MJ Hakeem, V Selamneni… - Journal of …, 2021 - Springer
Antibiotic resistance is spreading rapidly around the world and seriously impeding efforts to
control microbial infections. Although nucleic acid testing is widely deployed for the …
control microbial infections. Although nucleic acid testing is widely deployed for the …
CRISPR-based diagnosis of infectious and noninfectious diseases
S Jolany Vangah, C Katalani, HA Boone… - Biological procedures …, 2020 - Springer
Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity
which enables prokaryotes to detect any foreign DNA and then destroy it, has gained …
which enables prokaryotes to detect any foreign DNA and then destroy it, has gained …
Applications and challenges of CRISPR-Cas gene-editing to disease treatment in clinics
W Liu, L Li, J Jiang, M Wu, P Lin - Precision clinical medicine, 2021 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems
(Cas) are efficient tools for targeting specific genes for laboratory research, agricultural …
(Cas) are efficient tools for targeting specific genes for laboratory research, agricultural …
Electrochemical diagnostics of infectious viral diseases: Trends and challenges
Infectious diseases caused by viruses can elevate up to undesired pandemic conditions
affecting the global population and normal life function. These in turn impact the established …
affecting the global population and normal life function. These in turn impact the established …
Cross-species RNA-seq for deciphering host–microbe interactions
AJ Westermann, J Vogel - Nature Reviews Genetics, 2021 - nature.com
The human body is constantly exposed to microorganisms, which entails manifold
interactions between human cells and diverse commensal or pathogenic bacteria. The …
interactions between human cells and diverse commensal or pathogenic bacteria. The …
Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection
Host: pathogen interactions dictate the outcome of infection, yet the limitations of current
approaches leave large regions of this interface unexplored. Here, we develop a novel …
approaches leave large regions of this interface unexplored. Here, we develop a novel …