CRISPR/Cas9 landscape: Current state and future perspectives

M Tyumentseva, A Tyumentsev, V Akimkin - International Journal of …, 2023 - mdpi.com
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 is a unique
genome editing tool that can be easily used in a wide range of applications, including …

Reverse transcription-loop-mediated isothermal amplification-CRISPR-Cas13a technology as a promising diagnostic tool for SARS-CoV-2

C Ortiz-Cartagena, L Fernández-García… - Microbiology …, 2022 - Am Soc Microbiol
At the end of 2019, a new coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), caused a pandemic that persists to date and has resulted in more than 6.2 …

Novel nucleic acid detection strategies based on CRISPR‐Cas systems: From construction to application

C Zhu, C Liu, X Qiu, S Xie, W Li… - Biotechnology and …, 2020 - Wiley Online Library
Beyond their widespread application as genome‐editing and regulatory tools, clustered
regularly interspaced short palindromic repeats (CRISPR)‐CRISPR‐associated (Cas) …

Programmable low-cost DNA-based platform for viral RNA detection

L Zhou, AR Chandrasekaran, JA Punnoose… - Science …, 2020 - science.org
Detection of viruses is critical for controlling disease spread. Recent emerging viral threats,
including Zika virus, Ebola virus, and SARS-CoV-2 responsible for coronavirus disease …

[HTML][HTML] CRISPR-Cas system: a promising diagnostic tool for Covid-19

S Ebrahimi, H Khanbabaei, S Abbasi… - Avicenna journal of …, 2022 - ncbi.nlm.nih.gov
More than a year has passed since the beginning of the 2019 novel coronavirus diseases
(COVID-19) pandemic which has created massive problems globally affecting all aspects of …

The use of CRISPR/Cas9 as a tool to study human infectious viruses

H Lin, G Li, X Peng, A Deng, L Ye, L Shi… - Frontiers in Cellular …, 2021 - frontiersin.org
Clustered regularly interspaced short palindromic repeats (CRISPR) systems are a set of
versatile gene-editing toolkit that perform diverse revolutionary functions in various fields of …

[PDF][PDF] RETRACTED: Optimizing sgRNA to Improve CRISPR/Cas9 Knockout Efficiency: Special Focus on Human and Animal Cell

S Shojaei Baghini, ZR Gardanova, AO Zekiy… - … in Bioengineering and …, 2021 - frontiersin.org
During recent years, clustered regularly interspaced short palindromic repeat
(CRISPR)/CRISPR-associated protein 9 (Cas9) technologies have been noticed as a rapidly …

Potential opportunities and challenges of deploying next generation sequencing and CRISPR-Cas systems to support diagnostics and surveillance towards malaria …

BM Lyimo, ZR Popkin-Hall, DJ Giesbrecht… - Frontiers in Cellular …, 2022 - frontiersin.org
Recent developments in molecular biology and genomics have revolutionized biology and
medicine mainly in the developed world. The application of next generation sequencing …

Translating CRISPR-Cas therapeutics: approaches and challenges

LS Tay, N Palmer, R Panwala, WL Chew… - The CRISPR …, 2020 - liebertpub.com
CRISPR-Cas clinical trials have begun, offering a first glimpse at how DNA and RNA
targeting could enable therapies for many genetic and epigenetic human diseases. The …

Application of CRISPR-Cas system in the diagnosis and therapy of ESKAPE infections

Y Qian, D Zhou, M Li, Y Zhao, H Liu, L Yang… - Frontiers in Cellular …, 2023 - frontiersin.org
Antimicrobial-resistant ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …