Background Microbial strain information databases provide valuable data for microbial basic
research and applications. However, they rarely contain information on the genetic …

Abstract The ESKAPE (Enterococcus spp., Staphylococcus aureus, Klebsiella pneumoniae,
Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) isolates both …

Oligonucleotides are key compounds widely used for research, diagnostics, and
therapeutics. The rapid increase in oligonucleotide-based applications, together with the …

Duchenne muscular dystrophy (DMD) is caused by the dystrophin gene mutations and is
one of the most common and lethal human hereditary disorders. A novel therapeutic …

As the basis of animal reproductive activity, normal spermatogenesis directly determines the
efficiency of livestock production. An in-depth understanding of spermatogenesis will greatly …

Detection and monitoring of viruses are essential for healthy plants and prosperity. Recent
development in CRISPR/Cas system in diagnosis has open an avenue well suited for …

Varicella-zoster virus (VZV) infects more than 90% of the population worldwide and has a
high incidence of postherpetic neuralgia in elderly patients, seriously affecting their quality of …

One of the most important health concerns in society is the development of pathogen-
causing nosocomial infections. Since the first discovery of antibiotics, bacterial infections …

DNA nanostructures are easy to design and construct, have good biocompatibility, and show
great potential in biosensing and drug delivery. Numerous distinctive and versatile DNA …

Despite care and the availability of effective antiretroviral treatment, some human
immunodeficiency virus (HIV)-infected individuals suffer from neurocognitive disorders …