The role of genetic and epigenetic regulation in Intestinal Fibrosis in Inflammatory Bowel Disease: a descending process or a programmed consequence?

S Jarmakiewicz-Czaja, A Sokal, K Ferenc, E Motyka… - Genes, 2023 - mdpi.com
Inflammatory bowel diseases (IBDs) are a group of chronic diseases characterized by
recurring periods of exacerbation and remission. Fibrosis of the intestine is one of the most …

Roles of NRF2 in fibrotic diseases: from mechanisms to therapeutic approaches

W Hao, M Li, Q Cai, S Wu, X Li, Q He, Y Hu - Frontiers in Physiology, 2022 - frontiersin.org
Fibrosis is a persistent inflammatory response that causes scarring and tissue sclerosis by
stimulating myofibroblasts to create significant quantities of extracellular matrix protein …

Endoscopic stenting in Crohn's disease-related strictures: a systematic review and meta-analysis of outcomes

S Chandan, BS Dhindsa, SR Khan… - Inflammatory bowel …, 2023 - academic.oup.com
Background Crohn's disease (CD) is a chronic progressive condition that is complicated by
intestinal or colonic stricture in nearly 30% of cases within 10 years of the initial diagnosis …

Creeping fat exhibits distinct Inflammation-specific adipogenic preadipocytes in Crohn's disease

N Hwang, D Kang, SJ Shin, BK Yoon, J Chun… - Frontiers in …, 2023 - frontiersin.org
Creeping fat (CrF) is an extraintestinal manifestation observed in patients with Crohn's
disease (CD). It is characterized by the accumulation of mesenteric adipose tissue (MAT) …

[HTML][HTML] Timing of individualized surgical intervention in Crohn's disease

K Xia, RY Gao, XC Wu, L Yin… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract with an
increasing incidence worldwide. Comprehensive therapy for CD focuses on symptom …

[PDF][PDF] 益生菌对克罗恩病患者肠道屏障功能和免疫调节的影响

张振, 李政国, 李倩, 朱彦杰, 李航 - 中国微生态学杂志, 2022 - cjm.dmu.edu.cn
目的研究益生菌对克罗恩病患者肠道屏障功能和免疫调节的影响, 为该类患者的治疗提供参考.
方法选择2018 年1 月至2020 年6 月我院收治的94 例克罗恩病患者进行前瞻性随机对照研究 …

Crohn's Disease Complicated by Rare Types of Intestinal Obstruction: Two Case Reports

K Xia, R Gao, X Wu, Y Ruan, J Wan, T Wu… - Frontiers in …, 2022 - frontiersin.org
Intestinal obstruction is one of the most common complications of Crohn's disease (CD),
jeopardizing the quality of life of patients. Numerous factors may contribute to intestinal …

乌司奴单抗治疗狭窄型克罗恩病1 例报道及文献回顾

邵晓晓, 史睿昕, 方晔, 王伟中, 蒋益 - 中华全科医学, 2023 - zhqkyx.net
克罗恩病(Crohn's disease, CD) 是一种病因不明的慢性肉芽肿性疾病, 可累及从口腔至肛门
消化道的任何部位. CD 常伴有多种并发症, 如肠腔狭窄, 肠瘘, 脓肿, 穿孔等 …

A Novel Cause of Bowel Obstruction in a Patient with Long‐Standing Crohn's Disease

SV Vedula, TP Nickerson… - Case Reports in …, 2021 - Wiley Online Library
Solitary fibrous tumors are rare tumors of mesenchymal origin. Although most often
observed in the lung pleura, they have been reported in varied extrapleural sites. A 70‐year …

The CCL2/CCR2 axis is related to primary non-response to infliximab therapy in patients with Crohn's disease

W Yongheng, S Weigang, C Mengfan, X Wang - 2023 - researchsquare.com
Background: Nearly 30% of patients with Crohn's disease (CD) are primary non-response
(PNR) to anti-tumor necrosis factor-α (TNF-α) therapy, however, the mechanisms still remain …