The advent of heme during evolution allowed organisms possessing this compound to
safely and efficiently carry out a variety of chemical reactions that otherwise were difficult or …

Denitrification is a distinct means of energy conservation, making use of N oxides as
terminal electron acceptors for cellular bioenergetics under anaerobic, microaerophilic, and …

The cyclic tetrapyrrole heme is used as a prosthetic group in a broad variety of different
proteins in almost all organisms. Often, it is essential for vital biochemical processes such as …

Haem is the prosthetic group of proteins involved in many processes, and is also a
regulatory molecule that mediates cellular responses to oxygen, iron and haem itself. Haem …

Abstract Hemes (a, b, c, and o) and heme d 1 belong to the group of modified tetrapyrroles,
which also includes chlorophylls, cobalamins, coenzyme F 430, and siroheme. These …

In living organisms heme is formed from the common precursor uroporphyrinogen III by
either one of two substantially different pathways. In contrast to eukaryotes and most …

Scientific progress of the last 30 years on ferrochelatase and heme biosynthesis is
summarized in this review by covering the literature related to over 100 original references …

Heme is an essential prosthetic group for many proteins involved in fundamental biological
processes in all three domains of life. In Eukaryota and Bacteria heme is formed via a …

Culture of Desulfovibrio vulgaris in a medium supplemented with 5-aminolevulinic acid and l-
methionine-methyl-d 3 resulted in the formation of porphyrins (sirohydrochlorin …

Haems are involved in many cellular processes in prokaryotes and0 eukaryotes. The
biosynthetic pathway leading to haem formation is, with few exceptions, well-conserved, and …