Drug therapies for acute lung injury (ALI) are far from satisfactory, primarily because drugs
cannot specifically target the lungs. Direct delivery of drugs to the deep alveolar regions by …

There is growing evidence that mesenchymal stem cell-derived extracellular vesicles and
exosomes can significantly improve the curative effect of oxidative stress-related diseases …

Reactive oxygen species (ROS), either derived from exogenous sources or overproduced
endogenously, can disrupt the body's antioxidant defenses leading to compromised redox …

Objectives Acute respiratory distress syndrome (ARDS) is characterized by an excessive
pulmonary inflammatory response. Pyroptosis is a newly form of programmed inflammatory …

Intracellular redox homeostasis is highly important for the physiological processes of living
organisms. Real-time monitoring of the dynamics of this intracellular redox process is pivotal …

The mitochondrial quality control of lung epithelial cells is disturbed during sepsis, which
contributes to abnormal mitochondrial function and acute lung injury. Melatonin is one of the …

Sepsis is a life-threatening condition caused by a dysregulated host response to infection.
Although our understanding in the pathophysiological features of sepsis has increased …

(-)-Epigallocatechin-3-gallate (EGCG) is a major polyphenol of green tea that possesses a
wide variety of actions. EGCG acts as a strong antioxidant which effectively scavenges …

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a common disease with
high morbidity and mortality, and its pathogenesis is believed to be related to oxidative …

Symptoms of COVID-19 range from asymptomatic/mild symptoms to severe illness and
death, consequence of an excessive inflammatory process triggered by SARS-CoV-2 …