Downregulation of SIRT3 Aggravates Lung Ischemia Reperfusion Injury by Increasing Mitochondrial Fission and Oxidative Stress through HIF‐1α‐Dependent …

C Liu, S Pei, H Dai, Z Liu, M Ye, H Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Lung ischemia‐reperfusion injury (LIRI) is a severe multifaceted pathological condition that
can lead to poor patient outcome where oxidative stress and the resulting inflammatory …

[HTML][HTML] Friend or foe? The roles of antioxidants in acute lung injury

Y Liu, S Zhou, D Xiang, L Ju, D Shen, X Wang, Y Wang - Antioxidants, 2021 - mdpi.com
Acute lung injury (ALI) is an acute hypoxic respiratory insufficiency caused by various intra-
and extra-pulmonary injury factors. The oxidative stress caused by excessive reactive …

YuPingFengSan ameliorates LPS-induced acute lung injury and gut barrier dysfunction in mice

Y Wang, Y Wang, J Ma, Y Li, L Cao, T Zhu, H Hu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Yupingfengsan (YPFS) is a traditional Chinese medicine
decoction. YPFS comprises Astragalus mongholicus Bunge (Huangqi), Atractylodes rubra …

Apocynin alleviates lung injury by suppressing NLRP3 inflammasome activation and NF-κB signaling in acute pancreatitis

H Jin, X Yang, K Zhao, F Mei, Y Zhou, Y You… - International …, 2019 - Elsevier
Mounting evidence has demonstrated that acute pancreatitis (AP) is one of the causes of
multiple organ damage. NADPH (nicotinamide adenine dinucleotide phosphate) act as a …

Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity

TI Kao, PJ Chen, YH Wang, HH Tseng… - British Journal of …, 2021 - Wiley Online Library
Background and Purpose Neutrophil overactivation is crucial in the pathogenesis of acute
lung injury (ALI). Bletinib (3, 3′‐dihydroxy‐2′, 6′‐bis (p‐hydroxybenzyl)‐5 …

Apelin-13-Mediated AMPK ameliorates endothelial barrier dysfunction in acute lung injury mice via improvement of mitochondrial function and autophagy

X Kong, D Lin, L Lu, L Lin, H Zhang, H Zhang - International …, 2021 - Elsevier
Maintaining the pulmonary endothelial barrier that prevents the exudation of inflammatory
factors and proteins is the key to the treatment of acute lung injury (ALI). Apelin-13 plays an …

Guben Qingfei decoction attenuates LPS-induced acute lung injury by modulating the TLR4/NF-κB and Keap1/Nrf2 signaling pathways

Z Zeng, Y Fu, M Li, Y Shi, Q Ding, S Chen - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Acute lung injury (ALI) is a life-threatening and
widespread disease, with exceptionally high morbidity and mortality rates. Unfortunately …

[HTML][HTML] Gut microbiota modulates bleomycin-induced acute lung injury response in mice

Y Yoon, CL Hrusch, N Fei, GM Barrón, KAM Mills… - Respiratory …, 2022 - Springer
Background Airway instillation of bleomycin (BLM) in mice is a widely used, yet challenging,
model for acute lung injury (ALI) with high variability in treatment scheme and animal …

Inhibitory effect of lactoferrin-coated zinc nanoparticles on SARS-CoV-2 replication and entry along with improvement of lung fibrosis induced in adult male albino rats

EM El-Fakharany, H El-Gendi, YA El-Maradny… - International Journal of …, 2023 - Elsevier
Severe acute respiratory syndrome 2019-new coronavirus (SARS-CoV-2) is a major global
challenge caused by a pandemic disease, named 'COVID-19'with no effective and selective …

[HTML][HTML] Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In …

K Shi, Y Xiao, Y Dong, D Wang, Y Xie, J Tu… - International Journal of …, 2022 - mdpi.com
Acute lung injury (ALI) is a syndrome caused by an excessive inflammatory response
characterized by intractable hypoxemia both inside and outside the lung, for which effective …