Lycium barbarum polysaccharide protects against LPS-induced ARDS by inhibiting apoptosis, oxidative stress, and inflammation in pulmonary endothelial cells

L Chen, W Li, D Qi, D Wang - Free Radical Research, 2018 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) is a heterogenous syndrome characterised by
diffuse alveolar damage, with an increase in lung endothelial and epithelial permeability …

[HTML][HTML] Activation of the mechanosensitive Ca2+ channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics

Q Lu, EA Zemskov, X Sun, H Wang, M Yegambaram… - Redox Biology, 2021 - Elsevier
Mechanical ventilation is a life-saving intervention in critically ill patients with respiratory
failure due to acute respiratory distress syndrome (ARDS), a refractory lung disease with an …

The suppressive effects of Mer inhibition on inflammatory responses in the pathogenesis of LPS-induced ALI/ARDS

M Fukatsu, H Ohkawara, X Wang, L Alkebsi… - Science …, 2022 - science.org
The pathogenesis of sepsis-induced acute lung injury (ALI)/acute respiratory distress
syndrome (ARDS) has not yet been fully elucidated. Growth arrest–specific 6 (Gas6) has …

[HTML][HTML] The mitochondrial redistribution of eNOS is involved in lipopolysaccharide induced inflammasome activation during acute lung injury

H Wang, X Sun, Q Lu, EA Zemskov, M Yegambaram… - Redox Biology, 2021 - Elsevier
Acute lung injury (ALI) is a devastating clinical syndrome with no effective therapies.
Inflammasome activation has been reported to play a critical role in the initiation and …

[HTML][HTML] Aerosol-administered adelmidrol attenuates lung inflammation in a murine model of acute lung injury

L Interdonato, R D'amico, M Cordaro, R Siracusa… - Biomolecules, 2022 - mdpi.com
Acute lung injury (ALI) is a common and devastating clinical disorder with a high mortality
rate and no specific therapy. The pathophysiology of ALI is characterized by increased …

Forsythiae Fructuse extracts alleviates LPS-induced acute lung injury in mice by regulating PPAR-γ/RXR-α in lungs and colons

J Wang, L Luo, X Zhao, X Xue, L Liao, Y Deng… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Forsythiae Fructuse (FF), the dried fruit of
Forsythia suspensa (Thunb.) Vahl, is used as a traditional Chinese medicine that has been …

Tomatidine improves pulmonary inflammation in mice with acute lung injury

WC Huang, SJ Wu, YL Chen, CF Lin… - Mediators of …, 2021 - Wiley Online Library
Tomatidine, which is isolated from green tomato, can ameliorate inflammation and oxidative
stress in cells and animal experiments and has been shown to improve airway inflammation …

[HTML][HTML] Effect of tiger milk mushroom (Lignosus rhinocerus) supplementation on respiratory health, immunity and antioxidant status: an open-label prospective study

ESS Tan, TK Leo, CK Tan - Scientific reports, 2021 - nature.com
Tiger milk mushroom (TMM; Lignosus rhinocerus) have been used for a long time by
indigenous communities in South East Asia regions as traditional medicine for different …

The impaired swim bladder via ROS-mediated inhibition of the Wnt/Hedgehog pathway in zebrafish embryos exposed to eight toxic chemicals and binary chemical …

Y Gao, P Yang - Chemosphere, 2023 - Elsevier
To comprehensively explore the potential toxicity of aquatic organisms exposed to
chlorinated or brominated flame retardants (BFRs) and metals mixtures, it is necessary to …

[HTML][HTML] Effects of tocilizumab and dexamethasone on the downregulation of proinflammatory cytokines and upregulation of antioxidants in the lungs in oleic acid …

F Terzi, B Demirci, İ Çınar, M Alhilal, HS Erol - Respiratory research, 2022 - Springer
Background Acute respiratory distress syndrome (ARDS) is a life-threatening disease
caused by the induction of inflammatory cytokines and chemokines in the lungs. There is a …