[HTML][HTML] Pharmacologic therapies of ARDS: From natural herb to nanomedicine

L Meng, X Liao, Y Wang, L Chen, W Gao… - Frontiers in …, 2022 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is a common critical illness in respiratory care
units with a huge public health burden. Despite tremendous advances in the prevention and …

Naringenin-loaded dipalmitoylphosphatidylcholine phytosome dry powders for inhaled treatment of acute lung injury

Z Yu, X Liu, H Chen, L Zhu - Journal of aerosol medicine and …, 2020 - liebertpub.com
Background: Acute lung injury is a severe respiratory disorder characterized by
overwhelming lung inflammation. Dipalmitoylphosphatidylcholine (DPPC) is the major lipid …

[HTML][HTML] Transcriptomic evidence that switching from tobacco to electronic cigarettes does not reverse damage to the respiratory epithelium

GL Pozuelos, M Kagda, MA Rubin, ML Goniewicz… - Toxics, 2022 - mdpi.com
The health benefits of switching from tobacco to electronic cigarettes (ECs) are neither
confirmed nor well characterized. To address this problem, we used RNA-seq analysis to …

Co-administration of Luteolin mitigated toxicity in rats' lungs associated with doxorubicin treatment

SE Owumi, SO Nwozo, UO Arunsi, AK Oyelere… - Toxicology and applied …, 2021 - Elsevier
Doxorubicin (DOX), is a drug against lung malignancies with undesirable side effect
including oxidative, inflammatory and apoptotic effects. Luteolin (LUT), present in fruits and …

[HTML][HTML] Modulating the antioxidant response for better oxidative stress-inducing therapies: How to take advantage of two sides of the same medal?

P Shaw, N Kumar, M Sahun, E Smits, A Bogaerts… - Biomedicines, 2022 - mdpi.com
Oxidative stress-inducing therapies are characterized as a specific treatment that involves
the production of reactive oxygen and nitrogen species (RONS) by external or internal …

Chlorogenic acid abates oxido-inflammatory and apoptotic responses in the liver and kidney of Tamoxifen-treated rats

SE Owumi, JK Olusola, UO Arunsi… - Toxicology …, 2021 - academic.oup.com
Plant-derived phenolics are utilized as chemopreventive agents to abate adverse toxic
responses associated with drug-induced damages. Tamoxifen (TAM)—a chemotherapeutic …

[HTML][HTML] Terretonin as a new protective agent against sepsis-induced acute lung injury: Impact on SIRT1/Nrf2/NF-κBp65/NLRP3 signaling

GA Mohamed, SRM Ibrahim, DS El-Agamy, WM Elsaed… - Biology, 2021 - mdpi.com
Simple Summary Acute lung injury (ALI) is a severe inflammatory pulmonary disorder that
still causes a high mortality rate. As the current therapeutic strategies have not been effective …

Herbal active ingredients: potential for the prevention and treatment of acute lung injury

WY Yu, CX Gao, HH Zhang, YG Wu… - BioMed Research …, 2021 - Wiley Online Library
Acute lung injury (ALI) is a life‐threatening clinical syndrome with high morbidity and
mortality. The main pathological features of ALI are increased alveolar‐capillary membrane …

[HTML][HTML] Antioxidants as therapeutic agents in acute respiratory distress syndrome (ARDS) treatment—From mice to men

A von Knethen, U Heinicke, V Laux, MJ Parnham… - Biomedicines, 2022 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a major cause of patient mortality in intensive
care units (ICUs) worldwide. Considering that no causative treatment but only symptomatic …

[HTML][HTML] Mitochondrial damage–associated molecular patterns released by lung transplants are associated with primary graft dysfunction

D Scozzi, M Ibrahim, F Liao, X Lin, HM Hsiao… - American Journal of …, 2019 - Elsevier
Primary graft dysfunction (PGD) is a major limitation in short-and long-term lung transplant
survival. Recent work has shown that mitochondrial damage–associated molecular patterns …