Acute lung injury (ALI) is a life‐threatening clinical syndrome with high morbidity and
mortality. The main pathological features of ALI are increased alveolar‐capillary membrane …

Primary graft dysfunction (PGD) is a major limitation in short-and long-term lung transplant
survival. Recent work has shown that mitochondrial damage–associated molecular patterns …

Background Acute respiratory distress syndrome (ARDS) is a life-threatening disease
caused by the induction of inflammatory cytokines and chemokines in the lungs. There is a …

Lp-PLA2 is an enzyme encoded by the PLA2G7 gene located at chromosome 6p12-21,
which is included in different signal transduction pathways. The potential of serum levels of …

Acute respiratory distress syndrome (ARDS) is a major cause of patient mortality in intensive
care units (ICUs) worldwide. Considering that no causative treatment but only symptomatic …

Background As an organelle essential for intracellular energy supply, mitochondria are
involved in intracellular metabolism and inflammation, and cell death. The interaction of …

Significance: Increased endothelial permeability and inflammation are two major hallmarks
of the life-threatening conditions such as acute respiratory distress syndrome and sepsis …

Sivelestat sodium (SIV), a neutrophil elastase inhibitor, is mainly used for the clinical
treatment of acute respiratory distress syndrome (ARDS) or acute lung injury (ALI). However …

Acute respiratory distress syndrome (ARDS) is a life-threatening pulmonary condition
characterized by the sudden onset of respiratory failure, pulmonary edema, dysfunction of …

Paraquat (PQ), a highly toxic herbicide and primary attack for lung, results in severe acute
lung injury (ALI) appeared as evident oxidative stress, inflammation, and apoptosis …