Parkinson's disease (PD) is a neurological movement disorder primarily resulting from
damage to the nigrostriatal dopaminergic pathway. To elucidate the pathogenesis …

Most neurodegenerative disorders (NDD s) are characterized by cognitive impairment and
other neurological defects. The definite cause of and pathways underlying the progression …

The endocannabinoid system (ECS) is ubiquitous in most human tissues, and involved in
the regulation of mental health. Consequently, its dysregulation is associated with …

As a consequence of an increasingly aging population, the number of people affected by
neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease and …

Acetylcholine (ACh) is one of the most important neurotransmitters in the central cholinergic
system; it specifically binds to muscarinic and nicotinic receptors and is degraded by …

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …

Parkinson's disease (PD) is characterized by the degeneration of dopamine (DA) neurons in
the substantia nigra pars compacta, and motor symptoms including bradykinesia, rigidity …

Memory and motor deficits are commonly identified in Parkinson's disease (PD). 1-Methyl-4-
phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) is transformed to MPP+ via monoamine oxidase …

Parkinson's disease (PD) is classically characterized by motor symptoms; however, non-
motor symptoms (NMS) are increasingly recognized as relevant in disease-state, given the …

Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
about 1% of the population older than 60 years. Classically, PD is considered as a …