The role of epidermal growth factor and its receptors in mammalian CNS

RWC Wong, L Guillaud - Cytokine & growth factor reviews, 2004 - Elsevier
Epidermal growth factor (EGF) is a common mitogenic factor that stimulates the proliferation
of different types of cells, especially fibroblasts and epithelial cells. EGF activates the EGF …

The Colletotrichum lagenarium MAP Kinase Gene CMK1 Regulates Diverse Aspects of Fungal Pathogenesis

Y Takano, T Kikuchi, Y Kubo, JE Hamer… - Molecular Plant …, 2000 - Am Phytopath Society
The infection process of Colletotrichum lagenarium, the causal agent of cucumber
anthracnose disease, involves several key steps: germination; formation of melanized …

Sef is a spatial regulator for Ras/MAP kinase signaling

S Torii, M Kusakabe, T Yamamoto, M Maekawa… - Developmental cell, 2004 - cell.com
Spatiotemporal control of the Ras/ERK MAP kinase signaling pathway is among the key
mechanisms for regulating a wide variety of cellular processes. In this study, we report that …

Growth factors in breast cancer

RB Dickson, ME Lippman - Endocrine reviews, 1995 - academic.oup.com
I. Regulation of Mammary Cell Growth and Apoptosis A. Hormonal control of mammary
development, proliferation, and lactational defferentation D EVELOPMENT of the normal …

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

JR Riesgo-Escovar, M Jenni, A Fritz… - Genes & …, 1996 - genesdev.cshlp.org
We cloned and characterized the Drosophila homolog of mammalian Jun-N-terminal
kinases (DJNK). We show that DJNK is encoded by basket (bsk). Like hemipterous (hep) …

ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1

T Harada, T Morooka, S Ogawa, E Nishida - Nature cell biology, 2001 - nature.com
The classical mitogen-activated protein kinase (MAPK; also known as extracellular-signal-
regulated kinase), ERK cascade has been shown to have a crucial role in cell proliferation …

TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase

K Shirakabe, K Yamaguchi, H Shibuya, K Irie… - Journal of Biological …, 1997 - ASBMB
Ceramide has been proposed as a second messenger molecule implicated in a variety of
biological processes. It has recently been reported that ceramide activates stress-activated …

Differentiation and transforming growth factor-β receptor down-regulation by collagen-α2β1 integrin interaction is mediated by focal adhesion kinase and its …

Y Takeuchi, M Suzawa, T Kikuchi, E Nishida… - Journal of Biological …, 1997 - ASBMB
Interaction of type I collagen (COL (I)) with α2β1 integrin causes differentiation and
transforming growth factor (TGF)-β receptor down-regulation in osteoblastic cells (Takeuchi …

Antisense research and applications

ST Crooke, B Lebleu - 1993 - books.google.com
Antisense Research and Applications is a comprehensive review of oligonucleotide
research covering molecular biological advances in this field, the current status of antisense …

Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced …

P Chen, H Xie, MC Sekar, K Gupta, A Wells - The Journal of cell biology, 1994 - rupress.org
We recently have demonstrated that EGF receptor (EGFR)-induced cell motility requires
receptor kinase activity and autophosphorylation (P. Chen, K. Gupta, and A. Wells. 1994. J …