Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

Understanding of the basis of osteoarthritis (OA) has seen some interesting advancements
in recent years. It has been observed that cartilage degeneration is preceded by …

Osteoporosis or porous bone disorder is the result of an imbalance in an otherwise highly
balanced physiological process known as 'bone remodeling'. The immune system is …

Subchondral bone and the synovium play an important role in the initiation and progression
of OA. MRI often permits an early detection of synovial hypertrophy and bone marrow …

There is a well-established historical observation that structural joint damage by plain X-ray
correlates poorly with symptomatic disease in osteoarthritis (OA). This is often attributed to …

Subchondral bone remodelling is an integral part of osteoarthritis and involves the
development of subchondral sclerosis seen on plain imaging, along with osteophyte …

Mast cells and basophils are key contributors to allergies and other inflammatory diseases
since they are the most prominent source of histamine as well as numerous additional …

Osteoarthritis is characterized by articular cartilage breakdown, and emerging evidence
suggests that dysregulated innate immunity is likely involved. Here, we performed …

This study aimed to find potential diagnostic markers for osteoarthritis (OA) and analyze the
role of immune cells infiltration in this pathology. We used OA datasets from the Gene …

Abstract Purpose of the Review Mounting evidence supports a role of low-grade
inflammation in the pathophysiology of osteoarthritis (OA). We review and discuss the role of …