[HTML][HTML] Microfluidic and microscale assays to examine regenerative strategies in the neuro retina

M Vazquez - Micromachines, 2020 - mdpi.com
Bioengineering systems have transformed scientific knowledge of cellular behaviors in the
nervous system (NS) and pioneered innovative, regenerative therapies to treat adult neural …

[HTML][HTML] Glutamatergic neurons differentiated from embryonic stem cells: an investigation of differentiation and associated diseases

JH Chuang, WC Yang, Y Lin - International journal of molecular sciences, 2021 - mdpi.com
Neurons that have been derived from various types of stem cells have recently undergone
significant study due to their potential for use in various aspects of biomedicine. In particular …

[HTML][HTML] Human Brain In Vitro Model for Pathogen Infection-Related Neurodegeneration Study

Y Yan, AN Cho - International Journal of Molecular Sciences, 2024 - mdpi.com
Recent advancements in stem cell biology and tissue engineering have revolutionized the
field of neurodegeneration research by enabling the development of sophisticated in vitro …

整合设计策略下的工程化类器官与类器官芯片技术

胡可儿, 王汉奇, 黄儒麒, 张灿阳, 邢新会, 马少华 - 合成生物学, 2024 - synbioj.cip.com.cn
类器官和类器官芯片技术是一种由干细胞或特定类型的细胞在体外培养而成的模拟真实器官
功能和微环境的三维组织结构, 帮助研究者更准确地研究生物过程, 疾病机制 …

3D Bioprinting: an innovative technique for biofabrication applied to regenerative medicine and tissue engineering

MC Teixeira, KK Singh, BAG de Melo… - Nanotechnology and …, 2023 - Elsevier
Bioprinting is an innovative technology, which has received growing interest worldwide
within the pharmaceutical and biomedical medicine fields, mainly because of its broad …

hiPSC-derived 3D bioprinted skeletal muscle tissue implants regenerate skeletal muscle following volumetric muscle loss

YA Jodat, T Zhang, Z Al Tanoury, T Kamperman, K Shi… - 2021 - research.utwente.nl
Engineering of biomimetic tissue implants provides an opportunity for repairing volumetric
muscle loss (VML), beyond a tissue's innate repair capacity. Here, we present thick …

Initiating and Facilitating Brain Repair: Factors, Principles, and Mechanisms

LN Zamproni, MA Porcionatto - Regenerative Medicine and Brain Repair, 2024 - Springer
Introduction: Acute injuries to the brain result in a wide range of sequelae, and several
factors contribute to the severity of a brain lesion, including age, overall health, and …

[HTML][HTML] Building on a Solid Foundation: Adding Relevance and Reproducibility to Neurological Modeling Using Human Pluripotent Stem Cells

E Knock, LM Julian - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
The brain is our most complex and least understood organ. Animal models have long been
the most versatile tools available to dissect brain form and function; however, the human …

Integrated Design Strategies for Engineered Organoids and Organ-on-a-Chip Technologies

HU Keer, W Hanqi, CZ Ruqi HUANG… - Synthetic Biology …, 2024 - synbioj.cip.com.cn
Organoid and organ-on-a-chip technologies are three-dimensional tissue structures that are
cultivated in vitro from stem cells or tissue-derived primary cells. They replicate the functions …

Harnessing Thermogel Actuation for Driving Directional Stromal Cell Communication and Migration into Columnar Arrays

A Vernengo, A Pylostomou, J Wychowaniec, R Tognato… - 2024 - researchsquare.com
During developmental processes, cells frequently condense along a preferred axis, creating
columnar arrangements—a pivotal step in shaping elongating tissue structures and …